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AB144561

Dinaline, Antineoplastic agent

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(1 Publication)

MW 227.26 Da, Purity >98%. Antineoplastic agent. CI-994 precursor (ab142098). Induces reversible changes in amino acid transport, protein metabolism and DNA synthesis. Shows antiproliferative effects and antitumor effects in vivo.

View Alternative Names

2410064E05Rik, ACLS, AHR_HUMAN, AI195561, AI838772, AIS, ANDR_HUMAN, AR, AR8, AW493413, Ah receptor, Androgen nuclear receptor variant 2, Androgen receptor, Androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease), Antigen NY-CO-13, Aromatic hydrocarbon receptor, Aryl hydrocarbon receptor, Aryl hydrocarbon receptor precursor, Atherosclerosis, susceptibility to, included, BCC7, BXR, Cellular tumor antigen p53, Class E basic helix-loop-helix protein 76, DHTR, DKFZp686N23123, DNA binding protein, Dihydro testosterone receptor, Dihydrotestosterone receptor (DHTR), DmRab9, ER, ER-alpha, ER-beta, ERR a, ERR-alpha, ERR1 protein, ERR1_HUMAN, ER[a], ER[b], ESR, ESR B, ESR BETA, ESR1_HUMAN, ESRA, ESRL 1, ESRR A, ESTR B, Era, Erb, Erb2, Estr, Estra, Estradiol Receptor alpha, Estradiol Receptor beta, Estradiol receptor, Estrogen Receptor 1, Estrogen Receptor 2, Estrogen receptor, Estrogen receptor 1 (alpha), Estrogen receptor 2 (ER beta), Estrogen receptor 2 ER beta, Estrogen receptor alpha, Estrogen receptor beta 4, Estrogen receptor related 1, Estrogen receptor-like 1, Estrogen resistance, included, Estrogen-related receptor alpha, Estrra, FLJ11090, FLJ92943, GCCR, GCPS, GCRST, GCR_HUMAN, GLI Kruppel family member GLI 3, GLI Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome), GLI family zinc finger 3, GLI3 C-terminally truncated form, GLI3 form of 190 kDa, GLI3 form of 83 kDa, GLI3 full length protein, GLI3-190, GLI3-83, GLI3FL, GLI3_HUMAN, GR, Glioma associated oncogene family zinc finger 3, Glucocorticoid receptor, Grl1, HD 7, HD 7B, HD 9, HDAC, HDAC 7B, HDAC 9B, HDAC 9FL, HDAC9_HUMAN, HDL cholesterol, augmented response of, to hormone replacement, included, HDRP, HGNC:348, HUMARA, HYSP1, Histone deacetylase 4/5 related protein, Histone deacetylase 7, Histone deacetylase 7B, Histone deacetylase 9, Histone deacetylase 9A, Histone deacetylase-related protein, KD, KIAA0744, Kennedy disease (KD), LFS1, MEF2 interacting transcription repressor protein, MEF2-interacting transcription repressor MITR, MGC104252, MGC112732, MITR, Mutant tumor protein 53, Myocardial infarction, susceptibility to, included, NPC, NPC1_HUMAN, NR1C3, NR1I2_HUMAN, NR3A1, NR3A2, NR3B1, NR3C4, Niemann Pick C1 protein precursor, Niemann Pick disease, type C1, Niemann-Pick C1 protein, Nuclear receptor subfamily 1 group C member 3, Nuclear receptor subfamily 1 group I member 2, Nuclear receptor subfamily 3 group A member 1, Nuclear receptor subfamily 3 group A member 2, Nuclear receptor subfamily 3 group B member 1, Nuclear receptor subfamily 3 group C member 1, Nuclear receptor subfamily 3 group C member 4, Nuclear receptor subfamily 3 group C member 4 (NR3C4), ONR 1, OTTHUMP00000017718, OTTHUMP00000017719, OTTHUMP00000215173, OTTHUMP00000215174, OTTHUMP00000215175, Oncogene GLI3, Orphan nuclear receptor PAR 1, Orphan nuclear receptor PXR, P53_HUMAN, PAP A, PAPB, PAR, PAR q, PPAR-gamma, PPARG2, PPARG_HUMAN, PPD IV, PRR, Peroxisome proliferator activated receptor gamma 2, Peroxisome proliferator-activated receptor gamma, Phosphoprotein p53, Pregnane X receptor, RAB9 member RAS oncogene family, RAB9A member RAS oncogene family, RAB9A_HUMAN, RAS ASSOCIATED PROTEIN RAB9, RNESTROR, RP24-311F12.2, Rab 9, Ras-related protein Rab-9A, SBMA, SCAN1, SMAX1, SXR, Sid6061p, Sid99, Spinal and bulbar muscular atrophy, Spinal and bulbar muscular atrophy (SBMA), Steroid and xenobiotic receptor, Steroid hormone receptor ERR1, TFM, TRP53, TYDP, TYDP1_HUMAN, Testicular Feminization (TFM), Tp53, Transcriptional activator GLI3, Transcriptional repressor GLI3R, Transformation related protein 53, Tumor protein 53, Tumor protein p53, Tumor suppressor p53, Tyr-DNA phosphodiesterase 1, Tyrosyl-DNA phosphodiesterase 1, Zinc finger protein GLI 3, androgen receptor splice variant 4b, bHLHe76, estrogen receptor related receptor alpha, glucocorticoid nuclear receptor variant 1, hERR1, nr3c1, nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor), p53 tumor suppressor, pregnane X nuclear receptor variant 2, tumor antigen p55

Key facts

CAS number

58338-59-3

Purity

>98%

Form

Solid

form

Molecular weight

227.26 Da

Molecular formula

C<sub>1</sub><sub>3</sub>H<sub>1</sub><sub>3</sub>N<sub>3</sub>O

PubChem

42725

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Soluble in ethanol to 25 mM (with warming)

Biochemical name

Dinaline

Biological description

Antineoplastic agent. CI-994 precursor (ab142098). Induces reversible changes in amino acid transport, protein metabolism and DNA synthesis. Shows antiproliferative effects and antitumor effects in vivo.

Canonical smiles

C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)N

InChi

InChI=1S/C13H13N3O/c14-10-7-5-9(6-8-10)13(17)16-12-4-2-1-3-11(12)15/h1-8H,14-15H2,(H,16,17)

InChiKey

QGMGHALXLXKCBD-UHFFFAOYSA-N

IUPAC Name

4-amino-N-(2-aminophenyl)benzamide

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months

Product protocols

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 14:5916 PubMed37739954

2023

YAP silencing by RB1 mutation is essential for small-cell lung cancer metastasis.

Applications

Unspecified application

Species

Unspecified reactive species

Zhengming Wu,Junhui Su,Fu-Long Li,Tao Chen,Jaimie Mayner,Adam Engler,Shenghong Ma,Qingquan Li,Kun-Liang Guan
View all publications

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