JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB141390

Dithiothreitol (DTT), reducing reagent

Be the first to review this product! Submit a review

|

(1 Publication)

Dithiothreitol (DTT) (ab141390) is a cell-permeable reducing reagent. Prevents oxidation of thiol groups. Protective and protein purification agent. MW: 154.3, Purity >99%.

- Supplied as 1M in H2O solution
- Can be used to make Laemmli SDS protein sample loading buffer for SDS-PAGE
1 Images
Chemical Structure - Dithiothreitol (DTT), reducing reagent (AB141390)
  • Chemical Structure

Lab

Chemical Structure - Dithiothreitol (DTT), reducing reagent (AB141390)

2D chemical structure image of ab141390, Dithiothreitol (DTT), reducing reagent

Key facts

CAS number

3483-12-3

Purity

>99%

Form

Liquid

form

Molecular weight

154.3 Da

Molecular formula

C<sub>4</sub>H<sub>1</sub><sub>0</sub>O<sub>2</sub>S<sub>2</sub>

PubChem

446094

Nature

Synthetic

Biochemical name

Dithiothreitol

Biological description

Cell-permeable reducing reagent. Prevents oxidation of thiol groups. Protective and protein purification agent. Active in vivo and in vitro.

Canonical smiles

C(C(C(CS)O)O)S

Isomeric smiles

C([C@H]([C@@H](CS)O)O)S

InChi

InChI=1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m1/s1

InChiKey

VHJLVAABSRFDPM-QWWZWVQMSA-N

IUPAC Name

(2S,3S)-1,4-bis(sulfanyl)butane-2,3-diol

style
left-column

Complementary Products

Sample Prep & Detection Kits

AB113474

Nuclear Extraction Kit

Functional Studies - Nuclear Extraction Kit (AB113474)

  • 5
  • 3
Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Sample Prep & Detection Kits

AB208572

Universal HIER antigen retrieval reagent (10X)

Immunohistochemistry - Universal HIER antigen retrieval reagent (10X) (AB208572)

  • 5
  • 1
Reagents, Controls & Accessories

AB64218

Hydrogen Peroxide Blocking Reagent

Immunohistochemistry (Frozen sections) - Hydrogen Peroxide Blocking Reagent (AB64218)

  • 5
  • 3
style
left-column

Product details

This product is manufactured by BioVision, an Abcam company and was previously called 1201 DTT. 1201-1 is the same size as the 1 ML size of ab141390.

Supplied in water (1 M).

style
left-column

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
The product can be stored for up to 12 months
style
left-column
style
left-column
style
left-column

Product protocols

style
left-column

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Cell reports 43:114406 PubMed38963759

2024

ALDH1A3-acetaldehyde metabolism potentiates transcriptional heterogeneity in melanoma.

Applications

Unspecified application

Species

Unspecified reactive species

Yuting Lu,Jana Travnickova,Mihaly Badonyi,Florian Rambow,Andrea Coates,Zaid Khan,Jair Marques,Laura C Murphy,Pablo Garcia-Martinez,Richard Marais,Pakavarin Louphrasitthiphol,Alex H Y Chan,Christopher J Schofield,Alex von Kriegsheim,Joseph A Marsh,Valeria Pavet,Owen J Sansom,Robert S Illingworth,E Elizabeth Patton
View all publications
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com