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AB144022

D,L-threo-PDMP, Glucosylceramide synthase inhibitor

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MW 427 Da, Purity >98%. Glucosylceramide synthase inhibitor. Antimalarial activity. Antileukemic activity in combination with tetrandrine (Asc 2464). Active in vitro.

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1 Images
Chemical Structure - D,L-threo-PDMP, Glucosylceramide synthase inhibitor (AB144022)
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Chemical Structure - D,L-threo-PDMP, Glucosylceramide synthase inhibitor (AB144022)

2D chemical structure image of ab144022, D,L-threo-PDMP, Glucosylceramide synthase inhibitor

Key facts

CAS number

109836-82-0

Purity

>98%

Form

Solid

form

Molecular weight

427 Da

Molecular formula

C<sub>2</sub><sub>3</sub>H<sub>3</sub><sub>9</sub>ClN<sub>2</sub>O<sub>3</sub>

PubChem

16219895

Nature

Synthetic

Solubility

Soluble in DMSO

Soluble in ethanol

Soluble in methanol

Soluble in chloroform

Biochemical name

d-threo-PDMP

Biological description

Glucosylceramide synthase inhibitor. Antimalarial activity. Antileukemic activity in combination with tetrandrine (Asc 2464). Active in vitro.

See similar compounds

Canonical smiles

CCCCCCCCCC(=O)NC(CN1CCOCC1)C(C2=CC=CC=C2)O.Cl

Isomeric smiles

CCCCCCCCCC(=O)N[C@H](CN1CCOCC1)[C@@H](C2=CC=CC=C2)O.Cl

InChi

InChI=1S/C23H38N2O3.ClH/c1-2-3-4-5-6-7-11-14-22(26)24-21(19-25-15-17-28-18-16-25)23(27)20-12-9-8-10-13-20;/h8-10,12-13,21,23,27H,2-7,11,14-19H2,1H3,(H,24,26);1H/t21-,23-;/m1./s1

InChiKey

HVJHJOYQTSEKPK-BLDCTAJRSA-N

IUPAC Name

N-[(1R,2R)-1-hydroxy-3-morpholin-4-yl-1-phenylpropan-2-yl]decanamide;hydrochloride

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Complementary Products

Biochemicals

AB144046

L-threo-PDMP

Chemical Structure - L-threo-PDMP (AB144046)

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  • 0
Primary Antibodies

AB7349

Anti-Myelin Basic Protein antibody [12] - Oligodendrocyte Marker

BOND RX™ Validated|Recombinant|Lab Essentials

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myelin Basic Protein antibody [12] - Oligodendrocyte Marker (AB7349)

  • 4
  • 23
Assay Kits

AB283387

Carbonic Anhydrase (CA) Inhibitor Screening Kit (Colorimetric)

Functional Studies - Carbonic Anhydrase (CA) Inhibitor Screening Kit (Colorimetric) (AB283387)

  • 0
  • 0
Primary Antibodies

AB137869

Anti-Tyrosine Hydroxylase antibody [EP1532Y] - Neuronal Marker

RabMAb|Recombinant|Lab Essentials|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Tyrosine Hydroxylase antibody [EP1532Y] - Neuronal Marker (AB137869)

  • 5
  • 9
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Product promise

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