MW 474.7 Da, Purity >98%. Endogenous glucosylceramide synthase inhibitor. Ceramide (ab141743, ab141745) structural analog. Blocks karyokinesis and reduces cyst production. Inhibits glucosylceramide synthesis.
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- Biochimica et biophysica acta 1585:172-82003Glucosylceramide synthase and apoptosis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesRichard J Bleicher,Myles C CabotPubMed 12531551
- Bioscience, biotechnology, and biochemistry 65:1369-782001Glucosylceramide synthesis inhibitors block pharmacologically induced dispersal of the Golgi and anterograde membrane flow from the endoplasmic reticulum: implication of sphingolipid metabolism in maintenance of the Golgi architecture and anterograde membrane flow.Applications:Unspecified applicationReactive species:Unspecified reactive speciesM Nakamura,N Kuroiwa,Y Kono,A TakatsukiPubMed 11471737
- Proceedings of the National Academy of Sciences of the United States of America 92:9181-51995Sphingolipid synthesis as a target for chemotherapy against malaria parasites.Applications:Unspecified applicationReactive species:Unspecified reactive speciesS A Lauer,N Ghori,K HaldarPubMed 7568097
Key facts
- CAS number
149022-18-4
- Purity
> 98%
- Molecular weight
474.7 Da
- Molecular formula
C29H50N2O3
- PubChem identifier
3008318
- Nature
Synthetic
Recommended products
MW 474.7 Da, Purity >98%. Endogenous glucosylceramide synthase inhibitor. Ceramide (ab141743, ab141745) structural analog. Blocks karyokinesis and reduces cyst production. Inhibits glucosylceramide synthesis.
Key facts
- CAS number
149022-18-4
- Purity
> 98%
- Molecular weight
474.7 Da
- Molecular formula
C29H50N2O3
- PubChem identifier
3008318
- Nature
Synthetic
- Biochemical name
(1R,2R)-1-phenyl-2-palmitoylamino-3-morpholino-1-propanol
- Biological description
Endogenous glucosylceramide synthase inhibitor. Ceramide (ab141743, ab141745) structural analog. Blocks karyokinesis and reduces cyst production. Inhibits glucosylceramide synthesis.
- Canonical SMILES
CCCCCCCCCCCCCCCC(=O)NC(CN1CCOCC1)C(C2=CC=CC=C2)O
- Isomeric SMILES
CCCCCCCCCCCCCCCC(=O)N[C@H](CN1CCOCC1)[C@@H](C2=CC=CC=C2)O
- InChI
InChI=1S/C29H50N2O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-17-20-28(32)30-27(25-31-21-23-34-24-22-31)29(33)26-18-15-14-16-19-26/h14-16,18-19,27,29,33H,2-13,17,20-25H2,1H3,(H,30,32)/t27-,29-/m1/s1
- InChIKey
OFBANDBMHLEMFA-XRKRLSELSA-N
- IUPAC name
N-[(1R,2R)-1-hydroxy-3-morpholin-4-yl-1-phenylpropan-2-yl]hexadecanamide
Storage
- Shipped at conditions
Ambient - Can Ship with Ice
- Appropriate long-term storage conditions
-20°C
- Storage information
Store under desiccating conditions, The product can be stored for up to 12 months
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Chemical Structure - D,L-threo-PPMP, Glucosylceramide synthase inhibitor (ab144023)
2D chemical structure image of ab144023, D,L-threo-PPMP, Glucosylceramide synthase inhibitor
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