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AB141269

DMPQ dihydrochloride, PDGFR beta inhibitor

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MW 339.2 Da, Purity >99%. Potent and selective β-type platelet derived growth factor receptor tyrosine kinase (PDGFRβ) inhibitor (IC50 = 80 nM). Shows >100-fold selectivity over EGFR, PKA, PKC, p56 and erbB2.

Also available in simple stock solutions (ab146732) - add 1 ml of water to get an exact, ready-to-use concentration.
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Chemical Structure - DMPQ dihydrochloride, PDGFR beta inhibitor (AB141269)
  • Chemical Structure

Lab

Chemical Structure - DMPQ dihydrochloride, PDGFR beta inhibitor (AB141269)

2D chemical structure image of ab141269, DMPQ dihydrochloride, PDGFRbeta inhibitor

Key facts

CAS number

1123491-15-5

Purity

>99%

Form

Solid

form

Molecular weight

339.2 Da

Molecular formula

C<sub>1</sub><sub>6</sub>H<sub>1</sub><sub>6</sub>Cl<sub>2</sub>N<sub>2</sub>O<sub>2</sub>

PubChem

45073427

Nature

Synthetic

Solubility

Soluble in water to 100 mM

Biochemical name

DMPQ Dihydrochloride

Biological description

Potent and selective β-type platelet derived growth factor receptor tyrosine kinase (PDGFRβ) inhibitor (IC50 = 80 nM). Shows >100-fold selectivity over EGFR, PKA, PKC, p56 and erbB2.

Also available in simple stock solutions (ab146732) - add 1 ml of water to get an exact, ready-to-use concentration.

Canonical smiles

COC1=CC2=C(C=C(C=N2)C3=CC=NC=C3)C(=C1)OC.Cl.Cl

InChi

InChI=1S/C16H14N2O2.2ClH/c1-19-13-8-15-14(16(9-13)20-2)7-12(10-18-15)11-3-5-17-6-4-11;;/h3-10H,1-2H3;2*1H

InChiKey

YBBAOKYVJCNJIV-UHFFFAOYSA-N

IUPAC Name

5,7-dimethoxy-3-pyridin-4-ylquinoline;dihydrochloride

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months
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Product protocols

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Product promise

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