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MW 339.2 Da, Purity >99%. Potent and selective β-type platelet derived growth factor receptor tyrosine kinase (PDGFRβ) inhibitor (IC50 = 80 nM). Shows >100-fold selectivity over EGFR, PKA, PKC, p56 and erbB2.

Also available in simple stock solutions (ab146732) - add 1 ml of water to get an exact, ready-to-use concentration.

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Images

Chemical Structure - DMPQ dihydrochloride, PDGFR beta inhibitor (AB141269), expandable thumbnail

Key facts

CAS number
1123491-15-5
Purity
> 99%
Form
Solid
Molecular weight
339.2 Da
Molecular formula
C16H16Cl2N2O2
PubChem identifier
45073427
Nature
Synthetic

Target data

Recommended products

MW 339.2 Da, Purity >99%. Potent and selective β-type platelet derived growth factor receptor tyrosine kinase (PDGFRβ) inhibitor (IC50 = 80 nM). Shows >100-fold selectivity over EGFR, PKA, PKC, p56 and erbB2.

Also available in simple stock solutions (ab146732) - add 1 ml of water to get an exact, ready-to-use concentration.

Key facts

Purity
> 99%
PubChem identifier
45073427
Solubility

Soluble in water to 100 mM.

Biochemical name
DMPQ Dihydrochloride
Biological description

Potent and selective β-type platelet derived growth factor receptor tyrosine kinase (PDGFRβ) inhibitor (IC50 = 80 nM). Shows >100-fold selectivity over EGFR, PKA, PKC, p56 and erbB2.

Also available in simple stock solutions (ab146732) - add 1 ml of water to get an exact, ready-to-use concentration.

Canonical SMILES
COC1=CC2=C(C=C(C=N2)C3=CC=NC=C3)C(=C1)OC.Cl.Cl
InChI
InChI=1S/C16H14N2O2.2ClH/c1-19-13-8-15-14(16(9-13)20-2)7-12(10-18-15)11-3-5-17-6-4-11;;/h3-10H,1-2H3;2*1H
InChIKey
YBBAOKYVJCNJIV-UHFFFAOYSA-N
IUPAC name
5,7-dimethoxy-3-pyridin-4-ylquinoline;dihydrochloride

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months

Product promise

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In the unlikely event of one of our products not working as expected, you are covered by our product promise.

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Terms & Conditions.

1 product image

  • Chemical Structure - DMPQ dihydrochloride, PDGFR beta inhibitor (ab141269), expandable thumbnail

    Chemical Structure - DMPQ dihydrochloride, PDGFR beta inhibitor (ab141269)

    2D chemical structure image of ab141269, DMPQ dihydrochloride, PDGFRbeta inhibitor

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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