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MW 339.2 Da, Purity >99%. Potent and selective β-type platelet derived growth factor receptor tyrosine kinase (PDGFRβ) inhibitor (IC50 = 80 nM). Shows >100-fold selectivity over EGFR, PKA, PKC, p56 and erbB2.

Also available in simple stock solutions (ab146732) - add 1 ml of water to get an exact, ready-to-use concentration.

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Key facts

CAS number

1123491-15-5

Purity

> 99%

Form

Solid

Molecular weight

339.2 Da

Molecular formula

C16H16Cl2N2O2

PubChem identifier

45073427

Nature

Synthetic

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MW 339.2 Da, Purity >99%. Potent and selective β-type platelet derived growth factor receptor tyrosine kinase (PDGFRβ) inhibitor (IC50 = 80 nM). Shows >100-fold selectivity over EGFR, PKA, PKC, p56 and erbB2.

Also available in simple stock solutions (ab146732) - add 1 ml of water to get an exact, ready-to-use concentration.

Key facts

Purity

> 99%

PubChem identifier

45073427

Biochemical name

DMPQ Dihydrochloride

Biological description

Potent and selective β-type platelet derived growth factor receptor tyrosine kinase (PDGFRβ) inhibitor (IC50 = 80 nM). Shows >100-fold selectivity over EGFR, PKA, PKC, p56 and erbB2.

Also available in simple stock solutions (ab146732) - add 1 ml of water to get an exact, ready-to-use concentration.

Canonical SMILES

COC1=CC2=C(C=C(C=N2)C3=CC=NC=C3)C(=C1)OC.Cl.Cl

InChI

InChI=1S/C16H14N2O2.2ClH/c1-19-13-8-15-14(16(9-13)20-2)7-12(10-18-15)11-3-5-17-6-4-11;;/h3-10H,1-2H3;2*1H

InChIKey

YBBAOKYVJCNJIV-UHFFFAOYSA-N

IUPAC name

5,7-dimethoxy-3-pyridin-4-ylquinoline;dihydrochloride

Storage

Shipped at conditions

Ambient - Can Ship with Ice

Appropriate long-term storage conditions

Ambient

Storage information

The product can be stored for up to 12 months

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

1 product image

  • Chemical Structure - DMPQ dihydrochloride, PDGFR beta inhibitor (ab141269), expandable thumbnail

    Chemical Structure - DMPQ dihydrochloride, PDGFR beta inhibitor (ab141269)

    2D chemical structure image of ab141269, DMPQ dihydrochloride, PDGFRbeta inhibitor

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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