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AB145212

Docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenoic acid, Anti-inflammatory agent

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MW 328.5 g/mol, Purity >98%. Abundant essential n-3 polyunsaturated fatty acid in the CNS, shown to play a major anti-inflammatory role. Prevents LPS-induced dendritic cell maturation, characterized by a lack of proinflammatory cytokine production. Improves the nitroso-redox balance and reduces VEGF-mediated angiogenic signaling in microvascular endothelial cells. Inhibits Aβ1-42 fibrillation and toxicity in vitro. Retinoid X receptor (RXR) ligand.
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Chemical Structure - Docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenoic acid, Anti-inflammatory agent (AB145212)
  • Chemical Structure

Lab

Chemical Structure - Docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenoic acid, Anti-inflammatory agent (AB145212)

2D chemical structure image of ab145212, Docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenoic acid, Anti-inflammatory agent

Key facts

CAS number

6217-54-5

Purity

>98%

Molecular weight

328.5 g/mol

Molecular formula

C<sub>2</sub><sub>2</sub>H<sub>3</sub><sub>2</sub>O<sub>2</sub>

Nature

Synthetic

Solubility

Soluble in ethanol

Biological description

Abundant essential n-3 polyunsaturated fatty acid in the CNS, shown to play a major anti-inflammatory role. Prevents LPS-induced dendritic cell maturation, characterized by a lack of proinflammatory cytokine production. Improves the nitroso-redox balance and reduces VEGF-mediated angiogenic signaling in microvascular endothelial cells. Inhibits Aβ1-42 fibrillation and toxicity in vitro. Retinoid X receptor (RXR) ligand.

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months

Product protocols

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