AB120939
DRB (Benzimidazole), Casein kinase II inhibitor
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(3 Publications)
MW 319.14 g/mol, Purity >98%. Casein kinase II inhibitor (Ki values are 23 and 48 μM for CKII and CKI, respectively). Inhibitor of RNA polymerase II transcription in vitro and in vivo. Shown to inhibit cyclin C/CDK8 (IC50 = 17 μM) and cyclin H/CDK7/p38 (IC50 = 18 μM) signaling.
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- Chemical Structure
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Chemical Structure - DRB (Benzimidazole), Casein kinase II inhibitor (AB120939)
2D chemical structure image of ab120939, DRB (Benzimidazole), Casein kinase II inhibitor
Properties and storage information
Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
Publications (3)
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Cell reports 30:3296-3311.e5 PubMed32160538
2020
Genomic Repeats Categorize Genes with Distinct Functions for Orchestrated Regulation.
Applications
Unspecified application
Species
Unspecified reactive species
J Yuyang Lu,Wen Shao,Lei Chang,Yafei Yin,Tong Li,Hui Zhang,Yantao Hong,Michelle Percharde,Lerui Guo,Zhongyang Wu,Lichao Liu,Wei Liu,Pixi Yan,Miguel Ramalho-Santos,Yujie Sun,Xiaohua Shen
Molecular cell 75:102-116.e9 PubMed31128943
2019
RNA Targets Ribogenesis Factor WDR43 to Chromatin for Transcription and Pluripotency Control.
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Unspecified application
Species
Unspecified reactive species
Xianju Bi,Yanhui Xu,Tong Li,Xinmin Li,Wenzhi Li,Wen Shao,Kaili Wang,Ge Zhan,Zhongyang Wu,Wei Liu,J Yuyang Lu,Liang Wang,Jicheng Zhao,Jiawei Wu,Jie Na,Guohong Li,Pilong Li,Xiaohua Shen
eLife 7: PubMed29845934
2018
The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.
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Unspecified application
Species
Unspecified reactive species
Tyler B Faust,Yang Li,Curtis W Bacon,Gwendolyn M Jang,Amit Weiss,Bhargavi Jayaraman,Billy W Newton,Nevan J Krogan,Iván D'Orso,Alan D Frankel
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