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AB141278

Dutasteride, dual 5alpha reductase type 1 and type 2 inhibitor

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MW 528.5 Da, Purity >99%. Selective, competitive dual 5α reductase type 1 and type 2 inhibitor. Blocks the conversion of testosterone into dihydrotestosterone. Shows antitumor effects in vivo. Orally active.
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Chemical Structure - Dutasteride, dual 5alpha reductase type 1 and type 2 inhibitor (AB141278)
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Chemical Structure - Dutasteride, dual 5alpha reductase type 1 and type 2 inhibitor (AB141278)

2D chemical structure image of ab141278, Dutasteride, dual 5alpha reductase type 1 and type 2 inhibitor

Key facts

CAS number

164656-23-9

Purity

>99%

Form

Solid

form

Molecular weight

528.5 Da

Molecular formula

C<sub>2</sub><sub>7</sub>H<sub>3</sub><sub>0</sub>F<sub>6</sub>N<sub>2</sub>O<sub>2</sub>

PubChem

6918296

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Soluble in ethanol to 50 mM

Biochemical name

Dutasteride

Biological description

Selective, competitive dual 5α reductase type 1 and type 2 inhibitor. Blocks the conversion of testosterone into dihydrotestosterone. Shows antitumor effects in vivo. Orally active.

Canonical smiles

CC12CCC3C(C1CCC2C(=O)NC4=C(C=CC(=C4)C(F)(F)F)C(F)(F)F)CCC5C3(C=CC(=O)N5)C

Isomeric smiles

C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C(=O)NC4=C(C=CC(=C4)C(F)(F)F)C(F)(F)F)CC[C@@H]5[C@@]3(C=CC(=O)N5)C

InChi

InChI=1S/C27H30F6N2O2/c1-24-11-9-17-15(4-8-21-25(17,2)12-10-22(36)35-21)16(24)6-7-19(24)23(37)34-20-13-14(26(28,29)30)3-5-18(20)27(31,32)33/h3,5,10,12-13,15-17,19,21H,4,6-9,11H2,1-2H3,(H,34,37)(H,35,36)/t15-,16-,17-,19+,21+,24-,25+/m0/s1

InChiKey

JWJOTENAMICLJG-QWBYCMEYSA-N

IUPAC Name

(1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-[2,5-bis(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide

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Secondary Antibodies

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Biochemicals

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Product promise

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