Skip to main content

MW 371.6 Da, Purity >97%.

Novel, potent dynamin I and II inhibitor (IC50 values are 0.56 and 5.4 μM respectively). Shows 4.4-fold selectivity for dynamin I. Highly potent inhibitor of clathrin mediated endocytosis (IC50 = 1.9 μM). Displays low cell toxicity.

Be the first to review this product! Submit a review

Images

Chemical Structure - Dynole® 2-24, Dynamin I and II inhibitor (AB141290), expandable thumbnail

Publications

Key facts

CAS number
1416313-72-8
Purity
> 97%
Form
Liquid
Molecular weight
371.6 Da
Molecular formula
C24H41N3
PubChem identifier
71546959
Nature
Synthetic

Target data

Recommended products

MW 371.6 Da, Purity >97%.

Novel, potent dynamin I and II inhibitor (IC50 values are 0.56 and 5.4 μM respectively). Shows 4.4-fold selectivity for dynamin I. Highly potent inhibitor of clathrin mediated endocytosis (IC50 = 1.9 μM). Displays low cell toxicity.

Key facts

Purity
> 97%
PubChem identifier
71546959
Biochemical name
Dynole 2-24
Biological description

Novel, potent dynamin I and II inhibitor (IC50 values are 0.56 and 5.4 μM respectively). Shows 4.4-fold selectivity for dynamin I. Highly potent inhibitor of clathrin mediated endocytosis (IC50 = 1.9 μM). Displays low cell toxicity.

Canonical SMILES
CCCCCCCCCCNCC1=CN(C2=CC=CC=C21)CCCN(C)C
InChI
InChI=1S/C24H41N3/c1-4-5-6-7-8-9-10-13-17-25-20-22-21-27(19-14-18-26(2)3)24-16-12-11-15-23(22)24/h11-12,15-16,21,25H,4-10,13-14,17-20H2,1-3H3
IUPAC name
N-[[1-[3-(dimethylamino)propyl]indol-3-yl]methyl]decan-1-amine

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions

Notes

Sold under exclusive licence from Children's Medical Research Institute and Newcastle Innovation Ltd. Dynole® is a trademark of Children's Medical Research Institute and Newcastle Innovation Ltd.

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

1 product image

  • Chemical Structure - Dynole® 2-24, Dynamin I and II inhibitor (ab141290), expandable thumbnail

    Chemical Structure - Dynole® 2-24, Dynamin I and II inhibitor (ab141290)

    2D chemical structure image of ab141290, Dynole® 2-24, Dynamin I and II inhibitor

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com