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AB120645

Edaravone (MCI-186), antioxidant

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(3 Publications)

MW 174.2 Da, Purity >99%. Free radical scavenger and potent antioxidant. Inhibits production of reactive oxygen species, apoptosis and the lipoxygenase system.
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Chemical Structure - Edaravone (MCI-186), antioxidant (AB120645)
  • Chemical Structure

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Chemical Structure - Edaravone (MCI-186), antioxidant (AB120645)

2D chemical structure image of ab120645, Edaravone (MCI-186), antioxidant

Key facts

CAS number

89-25-8

Purity

>99%

Form

Solid

form

Molecular weight

174.2 Da

Molecular formula

C<sub>1</sub><sub>0</sub>H<sub>1</sub><sub>0</sub>N<sub>2</sub>O

PubChem

4021

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Biochemical name

Edaravone

Biological description

Free radical scavenger and potent antioxidant. Inhibits production of reactive oxygen species, apoptosis and the lipoxygenase system.

Canonical smiles

CC1=NN(C(=O)C1)C2=CC=CC=C2

InChi

InChI=1S/C10H10N2O/c1-8-7-10(13)12(11-8)9-5-3-2-4-6-9/h2-6H,7H2,1H3

InChiKey

QELUYTUMUWHWMC-UHFFFAOYSA-N

IUPAC Name

5-methyl-2-phenyl-4H-pyrazol-3-one

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Proteins & Peptides

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Primary Antibodies

AB105459

Anti-WIPI2 antibody [2A2]

BOND RX™ Validated|KO Validated|Trial Size

Western blot - Anti-WIPI2 antibody [2A2] (AB105459)

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months
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Product protocols

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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Current biology : CB 29:3386-3401.e8 PubMed31588000

2019

Ultrasonic Neuromodulation via Astrocytic TRPA1.

Applications

Unspecified application

Species

Unspecified reactive species

Soo-Jin Oh,Jung Moo Lee,Hyun-Bum Kim,Jungpyo Lee,Sungmin Han,Jin Young Bae,Gyu-Sang Hong,Wuhyun Koh,Jea Kwon,Eun-Sang Hwang,Dong Ho Woo,Inchan Youn,Il-Joo Cho,Yong Chul Bae,Sungon Lee,Jae Wan Shim,Ji-Ho Park,C Justin Lee

Biological & pharmaceutical bulletin 39:1300-8 PubMed27193377

2016

Ursodeoxycholic Acid Ameliorated Diabetic Nephropathy by Attenuating Hyperglycemia-Mediated Oxidative Stress.

Applications

Unspecified application

Species

Unspecified reactive species

Aili Cao,Li Wang,Xia Chen,Hengjiang Guo,Shuang Chu,Xuemei Zhang,Wen Peng

Neurochemistry international 90:134-41 PubMed26232623

2015

Edaravone leads to proteome changes indicative of neuronal cell protection in response to oxidative stress.

Applications

Unspecified application

Species

Unspecified reactive species

Mohammad-Saeid Jami,Zahra Salehi-Najafabadi,Fereshteh Ahmadinejad,Esthelle Hoedt,Morteza Hashemzadeh Chaleshtori,Mahdi Ghatrehsamani,Thomas A Neubert,Jan Petter Larsen,Simon Geir Møller
View all publications
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