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MW 512.6 Da, Purity >98%. Selective, irreversible elastase inhibitor. Inhibits succinyltrialanine p-nitroanilide hydrolytic enzyme (IC50 = 17 μM, porcine liver). Inhibits neutrophil and microglial elastase. Shows antiviral effects.

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Key facts

CAS number
51798-45-9
Purity
> 98%
Molecular weight
512.6 Da
Molecular formula
C21H36N8O7
PubChem identifier
91645
Nature
Synthetic

Target data

Recommended products

MW 512.6 Da, Purity >98%. Selective, irreversible elastase inhibitor. Inhibits succinyltrialanine p-nitroanilide hydrolytic enzyme (IC50 = 17 μM, porcine liver). Inhibits neutrophil and microglial elastase. Shows antiviral effects.

Key facts

Purity
> 98%
PubChem identifier
91645
Solubility

Soluble in water to 10 mM.

Biochemical name
(((S)-1-((S)-2-amino-1,4,5,6-tetrahydropyrimidin-4-yl)-2-(((S)-5-amino-1,5-dioxo-1-(((S)-1-oxopropan-2-yl)amino)pentan-2-yl)amino)-2-oxoethyl)carbamoyl)-L-leucine
Biological description

Selective, irreversible elastase inhibitor. Inhibits succinyltrialanine p-nitroanilide hydrolytic enzyme (IC50 = 17 μM, porcine liver). Inhibits neutrophil and microglial elastase. Shows antiviral effects.

Canonical SMILES
CC(C)CC(C(=O)O)NC(=O)NC(C1CCN=C(N1)N)C(=O)NC(CCC(=O)N)C(=O)NC(C)C=O
Isomeric SMILES
C[C@@H](C=O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H]([C@@H]1CCN=C(N1)N)NC(=O)N[C@@H](CC(C)C)C(=O)O
InChI
InChI=1S/C21H36N8O7/c1-10(2)8-14(19(34)35)28-21(36)29-16(12-6-7-24-20(23)27-12)18(33)26-13(4-5-15(22)31)17(32)25-11(3)9-30/h9-14,16H,4-8H2,1-3H3,(H2,22,31)(H,25,32)(H,26,33)(H,34,35)(H3,23,24,27)(H2,28,29,36)/t11-,12-,13-,14-,16-/m0/s1
InChIKey
IJWCGVPEDDQUDE-YGJAXBLXSA-N
IUPAC name
(2S)-2-[[(1S)-2-[[(2S)-5-amino-1,5-dioxo-1-[[(2S)-1-oxopropan-2-yl]amino]pentan-2-yl]amino]-1-[(6S)-2-amino-1,4,5,6-tetrahydropyrimidin-6-yl]-2-oxoethyl]carbamoylamino]-4-methylpentanoic acid

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions, The product can be stored for up to 12 months

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