Enalaprilat, Angiotensin II converting enzyme inhibitor

Key facts

CAS number

1187075-34-8

Purity

>99%

Form

Solid

form

Molecular weight

384.4 Da

Molecular formula

C₁₈H₂₈N₂O₇

PubChem

21585234

Nature

Synthetic

Solubility

Soluble in water to 10 mM (with warming)

Soluble in DMSO to 100 mM (with warming)

Biochemical name

1-[2-[(1-Carboxy-3-phenylpropyl)amino]propanoyl]pyrrolidine-2-carboxylic acid;dihydrate

Biological description

Angiotensin II converting enzyme inhibitor. Inhibits angiotensin II-induced cardiac fibroblast proliferation. Active metabolite of Enalapril (ab141929). Antihypertensive agent. Active in vivo and in vitro.

Canonical smiles

CC(C(=O)N1CCCC1C(=O)O)NC(CCC2=CC=CC=C2)C(=O)O.O.O

InChi

InChI=1S/C18H24N2O5.2H2O/c1-12(16(21)20-11-5-8-15(20)18(24)25)19-14(17(22)23)10-9-13-6-3-2-4-7-13;;/h2-4,6-7,12,14-15,19H,5,8-11H2,1H3,(H,22,23)(H,24,25);2*1H2

InChiKey

MZYVOFLIPYDBGD-UHFFFAOYSA-N

IUPAC Name

1-[2-[(1-carboxy-3-phenylpropyl)amino]propanoyl]pyrrolidine-2-carboxylic acid;dihydrate