MW 588.6 Da, Purity >98%. Topoisomerase II inhibitor. Anticancer agent. Achieve your results faster with highly validated, pure and trusted compounds.
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- Frontiers in veterinary science 10:11549872023Influence of Rho/ROCK inhibitor Y-27632 on proliferation of equine mesenchymal stromal cells.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMichaela Melzer,Janina Burk,Deborah J Guest,Jayesh DudhiaPubMed 37346276
- Cell reports 40:1110972022Neuropilin-2 axis in regulating secretory phenotype of neuroendocrine-like prostate cancer cells and its implication in therapy resistance.Applications:Unspecified applicationReactive species:Unspecified reactive speciesRidwan Islam,Juhi Mishra,Navatha Shree Polavaram,Sreyashi Bhattacharya,Zhengdong Hong,Sanika Bodas,Sunandini Sharma,Alyssa Bouska,Tyler Gilbreath,Ahmed M Said,Lynette M Smith,Benjamin A Teply,Michael H Muders,Surinder K Batra,Kaustubh Datta,Samikshan DuttaPubMed 35858551
- Scientific reports 11:232212021Metabolite and thymocyte development defects in ADA-SCID mice receiving enzyme replacement therapy.Applications:Unspecified applicationReactive species:Unspecified reactive speciesFederico A Moretti,Giuliana Giardino,Teresa C H Attenborough,Athina Soragia Gkazi,Ben K Margetts,Giancarlo la Marca,Lynette Fairbanks,Tessa Crompton,H Bobby GasparPubMed 34853379
- Journal of leukocyte biology 110:343-3562020Inducing regulated necrosis and shifting macrophage polarization with anti-EMMPRIN antibody (161-pAb) and complement factors.Applications:Unspecified applicationReactive species:Unspecified reactive speciesNizar Hijaze,Max Ledersnaider,Elina Simanovich,Sameer Kassem,Michal A RahatPubMed 33205451
- Communications biology 3:2452020Tau affects P53 function and cell fate during the DNA damage response.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMartina Sola et. al.PubMed 32427887
- Nature 580:647-6522020AIM2 inflammasome surveillance of DNA damage shapes neurodevelopment.Applications:Unspecified applicationReactive species:Unspecified reactive speciesCatherine R Lammert et. al.PubMed 32350463
- Immunology letters 220:51-622020Etoposide-mediated depletion of peripheral blood monocytes post s.aureus infection attenuates septic arthritis by modulating macrophage-derived factors responsible for inflammatory destruction.Applications:Unspecified applicationReactive species:Unspecified reactive speciesSahin Sultana et. al.PubMed 32032616
- Cell reports 30:1235-1245.e42020The ARK Assay Is a Sensitive and Versatile Method for the Global Detection of DNA-Protein Crosslinks.Applications:Unspecified applicationReactive species:Unspecified reactive speciesQianghua Hu,Naeh Klages-Mundt,Rui Wang,Erica Lynn,Liton Kuma Saha,Huimin Zhang,Mrinal Srivastava,Xi Shen,Yanyan Tian,Hyeung Kim,Yin Ye,Tanya Paull,Shunichi Takeda,Junjie Chen,Lei LiPubMed 31995761
- Neuron 104:239-255.e122019CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons.Applications:Unspecified applicationReactive species:Unspecified reactive speciesRuilin Tian et. al.PubMed 31422865
Key facts
- CAS number
33419-42-0
- Purity
> 98%
- Form
Solid
- Molecular weight
588.6 Da
- Molecular formula
C29H32O13
- PubChem identifier
36462
- Nature
Synthetic
Target data
Recommended products
MW 588.6 Da, Purity >98%. Topoisomerase II inhibitor. Anticancer agent. Achieve your results faster with highly validated, pure and trusted compounds.
Key facts
- CAS number
33419-42-0
- Purity
> 98%
- Form
Solid
- Molecular weight
588.6 Da
- Molecular formula
C29H32O13
- PubChem identifier
36462
- Nature
Synthetic
- Solubility
Very soluble in methanol, chloroform; slightly soluble in ethanol, sparingly soluble in water. Water solubility: approx 0.08 mg/mL.
- Biochemical name
Etoposide
- Biological description
Topoisomerase II inhibitor. Anticancer agent.
- Canonical SMILES
CC1OCC2C(O1)C(C(C(O2)OC3C4COC(=O)C4C(C5=CC6=C(C=C35)OCO6)C7=CC(=C(C(=C7)OC)O)OC)O)O
- Isomeric SMILES
C[C@@H]1OC[C@@H]2[C@@H](O1)[C@@H]([C@H]([C@@H](O2)O[C@H]3[C@H]4COC(=O)[C@@H]4[C@@H](C5=CC6=C(C=C35)OCO6)C7=CC(=C(C(=C7)OC)O)OC)O)O
- InChI
InChI=1S/C29H32O13/c1-11-36-9-20-27(40-11)24(31)25(32)29(41-20)42-26-14-7-17-16(38-10-39-17)6-13(14)21(22-15(26)8-37-28(22)33)12-4-18(34-2)23(30)19(5-12)35-3/h4-7,11,15,20-22,24-27,29-32H,8-10H2,1-3H3/t11-,15+,20-,21-,22+,24-,25-,26-,27-,29+/m1/s1
- InChIKey
VJJPUSNTGOMMGY-MRVIYFEKSA-N
- IUPAC name
(5S,5aR,8aR,9R)-5-[[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl]oxy]-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one
Storage
- Shipped at conditions
Ambient - Can Ship with Ice
- Appropriate short-term storage conditions
Ambient
- Appropriate long-term storage conditions
Ambient
- Storage information
The product can be stored for up to 12 months
Product promise
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
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1 product image
Chemical Structure - Etoposide, Topoisomerase II inhibitor (ab120227)
2D chemical structure image of ab120227, Etoposide, Topoisomerase II inhibitor
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