Skip to main content

MW 262.35 g/mol. Potent, selective erastin-induced ferroptosis inhibitor (EC50 = 60 nM). Selectively inhibits Ras selective lethal compound-induced death. Blocks Artesunate (ab142829)-induced lipid peroxidation and cell death. Has no effect on CYP2E1 expression or cellular GSH level.

Be the first to review this product! Submit a review

Images

Chemical Structure - Ferrostatin 1, erastin-induced ferroptosis inhibitor (AB146169), expandable thumbnail

Publications

Key facts

CAS number
347174-05-4
Form
Solid
Molecular weight
262.35 g/mol
Molecular formula
C15H22N2O2
Nature
Synthetic

Recommended products

MW 262.35 g/mol. Potent, selective erastin-induced ferroptosis inhibitor (EC50 = 60 nM). Selectively inhibits Ras selective lethal compound-induced death. Blocks Artesunate (ab142829)-induced lipid peroxidation and cell death. Has no effect on CYP2E1 expression or cellular GSH level.

Key facts

Solubility

Soluble in DMSO (up to 100 mg/ml).

Soluble in Ethanol (up to 100 mg/ml).

Biological description

Potent, selective erastin-induced ferroptosis inhibitor (EC50 = 60 nM). Selectively inhibits Ras selective lethal compound-induced death. Blocks Artesunate (ab142829)-induced lipid peroxidation and cell death. Has no effect on CYP2E1 expression or cellular GSH level.

Canonical SMILES
O=C(OCC)C2CCC(NC1CCCCC1)C(N)C2
InChI
InChI=1S/C15H22N2O2/c1-2-19-15(18)11-8-9-14(13(16)10-11)17-12-6-4-3-5-7-12/h8-10,12,17H,2-7,16H2,1H3
InChIKey
UJHBVMHOBZBWMX-UHFFFAOYSA-N

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

1 product image

  • Chemical Structure - Ferrostatin 1, erastin-induced ferroptosis inhibitor (ab146169), expandable thumbnail

    Chemical Structure - Ferrostatin 1, erastin-induced ferroptosis inhibitor (ab146169)

    2D chemical structure image of ab146169, Ferrostatin 1, erastin-induced ferroptosis inhibitor

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com