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AB144253

Ferulenol, ATP synthesis inhibitor

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MW 366.5 Da, Purity >98%. ATP synthesis inhibitor. Potent antibiotic agent. Tubulin polymerization stimulator. Selective succinate ubiquinone reductase inhibitor. Induces mPTP opening and disrupts mitochondrial membrane potential. Shows cytotoxic effects against cancer cell lines. Shows more potent anticoagulant activity than warfarin (ab141979) in vivo. .
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Chemical Structure - Ferulenol, ATP synthesis inhibitor (AB144253)
  • Chemical Structure

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Chemical Structure - Ferulenol, ATP synthesis inhibitor (AB144253)

2D chemical structure image of ab144253, Ferulenol, ATP synthesis inhibitor

Key facts

CAS number

6805-34-1

Purity

>98%

Source

Ferula communis

Molecular weight

366.5 Da

Molecular formula

C<sub>2</sub><sub>4</sub>H<sub>3</sub><sub>0</sub>O<sub>3</sub>

PubChem

54679300

Nature

Native

Solubility

Soluble in ethanol

Soluble in DMSO

Biochemical name

Ferulenol

Biological description

ATP synthesis inhibitor. Potent antibiotic agent. Tubulin polymerization stimulator. Selective succinate ubiquinone reductase inhibitor. Induces mPTP opening and disrupts mitochondrial membrane potential. Shows cytotoxic effects against cancer cell lines. Shows more potent anticoagulant activity than warfarin (ab141979) in vivo.

Canonical smiles

CC(=CCCC(=CCCC(=CCC1=C(C2=CC=CC=C2OC1=O)O)C)C)C

Isomeric smiles

CC(=CCC/C(=C/CC/C(=C/CC1=C(C2=CC=CC=C2OC1=O)O)/C)/C)C

InChi

InChI=1S/C24H30O3/c1-17(2)9-7-10-18(3)11-8-12-19(4)15-16-21-23(25)20-13-5-6-14-22(20)27-24(21)26/h5-6,9,11,13-15,25H,7-8,10,12,16H2,1-4H3/b18-11+,19-15+

InChiKey

NJJDBBUWWOAOLD-CFBAGHHKSA-N

IUPAC Name

4-hydroxy-3-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienyl]chromen-2-one

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
It is important to note that this product is reported to be light sensitive|Store in the dark|Store under desiccating conditions
Handling instructions

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Product protocols

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