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AB120867

FFN202 (Mini 202), Fluorescent VMAT1 and VMAT2 substrate

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(4 Publications)

MW 353.68 g/mol, Purity >97%. Novel, pH responsive fluorescent false neurotransmitter (FFN). Rodent VMAT1 and VMAT2 substrate. Enables in situ pH measurement of secretory catecholamine vesicles in PC-12 cells. Sufficiently bright, photostable and suitable for two-photon fluorescence microscopy and standard fluorescent microscopy. Compatible with GFP tags.
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Chemical Structure - FFN202 (Mini 202), Fluorescent VMAT1 and VMAT2 substrate (AB120867)
  • Chemical Structure

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Chemical Structure - FFN202 (Mini 202), Fluorescent VMAT1 and VMAT2 substrate (AB120867)

2D chemical structure image of ab120867, FFN202 (Mini 202), Fluorescent VMAT1 and VMAT2 substrate

Key facts

CAS number

1234064-29-9

Purity

>97%

Form

Solid

form

Molecular weight

353.68 g/mol

Molecular formula

C<sub>1</sub><sub>1</sub>H<sub>1</sub><sub>0</sub>ClNO<sub>3</sub>.CF<sub>3</sub>CO<sub>2</sub>H

Nature

Synthetic

Solubility

Soluble in water to 50 mM

Biological description

Novel, pH responsive fluorescent false neurotransmitter (FFN). Rodent VMAT1 and VMAT2 substrate. Enables in situ pH measurement of secretory catecholamine vesicles in PC-12 cells. Sufficiently bright, photostable and suitable for two-photon fluorescence microscopy and standard fluorescent microscopy. Compatible with GFP tags.

IUPAC Name

3-(2-Aminoethyl)-6-chloro-7-hydroxy-2H-1-benzopyran-2-one 2,2,2-trifluoroacetate

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Publications (4)

Recent publications for all applications. Explore the full list and refine your search

The Journal of biological chemistry 294:9402-9415 PubMed31004036

2019

The priming factor CAPS1 regulates dense-core vesicle acidification by interacting with rabconnectin3β/WDR7 in neuroendocrine cells.

Applications

Unspecified application

Species

Unspecified reactive species

Ellen Crummy,Muralidharan Mani,John C Thellman,Thomas F J Martin

Scientific reports 9:2236 PubMed30783186

2019

Recycling endosomal CD133 functions as an inhibitor of autophagy at the pericentrosomal region.

Applications

Unspecified application

Species

Unspecified reactive species

Hideki Izumi,Yuanyuan Li,Masami Shibaki,Daisuke Mori,Michio Yasunami,Seiji Sato,Hisashi Matsunaga,Takao Mae,Kenji Kodama,Takehiko Kamijo,Yasuhiko Kaneko,Akira Nakagawara

Arteriosclerosis, thrombosis, and vascular biology 39:188-199 PubMed30567483

2018

Perivascular Adipocytes Store Norepinephrine by Vesicular Transport.

Applications

Unspecified application

Species

Unspecified reactive species

Maleeha F Ahmad,David Ferland,Nadia Ayala-Lopez,G Andres Contreras,Emma Darios,Janice Thompson,Alexander Ismail,Kyan Thelen,Adam J Moeser,Robert Burnett,Arun Anantharam,Stephanie W Watts

Scientific reports 6:27287 PubMed27264104

2016

Nanodisc-cell fusion: control of fusion pore nucleation and lifetimes by SNARE protein transmembrane domains.

Applications

Unspecified application

Species

Unspecified reactive species

Zhenyong Wu,Sarah M Auclair,Oscar Bello,Wensi Vennekate,Natasha R Dudzinski,Shyam S Krishnakumar,Erdem Karatekin
View all publications
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