Finasteride, Type II 5alpha-reductase inhibitor

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MW 372.5 Da, Purity >99%. Type II 5α-reductase inhibitor (IC₅₀ values are 11.3 and 313 nM at type II and type I respectively). Reduces prostate gland size. Suppresses conversion of testosterone to dihydrotestosterone. Active in vivo and orally active.

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3 beta and steroid delta isomerase 1, 3 beta and steroid hydroxy delta 5 steroid dehydrogenase, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I, 3 oxo 5 alpha steroid delta 4 dehydrogenase alpha 1, 3-beta-HSD I, 3-beta-hydroxy-5-ene steroid dehydrogenase, 3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1,5-alpha reductase, 3-oxo-5-alpha-steroid 4-dehydrogenase 1, 3-oxo-5-alpha-steroid 4-dehydrogenase 2, 3BETAHSD, 3BH, 3BHS1_HUMAN, 3BHSD, 5 alpha reductase, 5 alpha-SR2, 5ART2, ABC member 16, MDR/TAP subfamily, ABC16, ABCB1, ABCBB_HUMAN, ACLS, AIS, ANDR_HUMAN, AR, AR8, ATP binding cassette sub family B (MDR/TAP) member 11, ATP-binding cassette sub-family B member 11, Androgen nuclear receptor variant 2, Androgen receptor, Androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease), Atherosclerosis, susceptibility to, included, BRIC2, BXR, Bile salt export pump, Bsep, DHTR, DKFZp686N23123, DNA binding protein, Delta-5-3-ketosteroid isomerase, Dihydro testosterone receptor, Dihydrotestosterone receptor (DHTR), EC, ER, ER-alpha, ER-beta, ERR a, ERR-alpha, ERR1 protein, ERR1_HUMAN, ER[a], ER[b], ESR, ESR B, ESR BETA, ESR1_HUMAN, ESRA, ESRL 1, ESRR A, ESTR B, Era, Erb, Erb2, Estr, Estra, Estradiol Receptor alpha, Estradiol Receptor beta, Estradiol receptor, Estrogen Receptor 1, Estrogen Receptor 2, Estrogen receptor, Estrogen receptor 1 (alpha), Estrogen receptor 2 (ER beta), Estrogen receptor 2 ER beta, Estrogen receptor alpha, Estrogen receptor beta 4, Estrogen receptor related 1, Estrogen receptor-like 1, Estrogen resistance, included, Estrogen-related receptor alpha, Estrra, GCPS, GLI Kruppel family member GLI 3, GLI Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome), GLI family zinc finger 3, GLI3 C-terminally truncated form, GLI3 form of 190 kDa, GLI3 form of 83 kDa, GLI3 full length protein, GLI3-190, GLI3-83, GLI3FL, GLI3_HUMAN, Glioma associated oncogene family zinc finger 3, HDL cholesterol, augmented response of, to hormone replacement, included, HGNC:5217, HSD3B, HSDB3, HSDB3A, HUMARA, HYSP1, Hydroxy delta 5 steroid dehydrogenase, Hydroxy delta 5 steroid dehydrogenase 3 beta and steroid delta isomerase 1, IMD42, KD, Kennedy disease (KD), MGC129539, MGC138457, Micropenis, included, Myocardial infarction, susceptibility to, included, NF-E2-related factor 2, NF2L2_HUMAN, NR1B1, NR1F3, NR1I2_HUMAN, NR3A1, NR3A2, NR3B1, NR3C4, NRF2, Nfe2l2, Nuclear factor, Nuclear factor (erythroid derived 2) like 2, Nuclear factor erythroid 2-related factor 2, Nuclear factor erythroid derived 2 like 2, Nuclear mitotic apparatus protein retinoic acid receptor alpha fusion protein, Nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, Nuclear receptor subfamily 1 group B member 1, Nuclear receptor subfamily 1 group F member 3, Nuclear receptor subfamily 1 group I member 2, Nuclear receptor subfamily 3 group A member 1, Nuclear receptor subfamily 3 group A member 2, Nuclear receptor subfamily 3 group B member 1, Nuclear receptor subfamily 3 group C member 4, Nuclear receptor subfamily 3 group C member 4 (NR3C4), Nucleophosmin retinoic acid receptor alpha fusion protein NPM RAR long form, ONR 1, OTTHUMP00000017718, OTTHUMP00000017719, OTTHUMP00000215173, OTTHUMP00000215174, OTTHUMP00000215175, Oncogene GLI3, Orphan nuclear receptor PAR 1, Orphan nuclear receptor PXR, PAP A, PAPB, PAR, PAR q, PFIC 2, PGY4, PPD IV, PRR, Pregnane X receptor, Progesterone reductase, RAR, RAR related orphan nuclear receptor variant 2, RAR related orphan receptor C, isoform a, RAR related orphan receptor gamma, RAR-alpha, RAR-related orphan receptor C, RARA_HUMAN, RARalpha1, RNESTROR, RORG_HUMAN, RZR GAMMA, RZRG, Retinoic acid binding receptor gamma, Retinoic acid nuclear receptor alpha variant 1, Retinoic acid nuclear receptor alpha variant 2, Retinoic acid receptor alpha, Retinoic acid receptor alpha polypeptide, Retinoid-related orphan receptor-gamma, Rorc, S5A1_HUMAN, S5A2_HUMAN, S5AR, S5AR 1, S5AR 2, SBMA, SDR11E1, SMAX1, SR type 1, SR type 2, SXR, Sister of P glycoprotein, Spgp, Spinal and bulbar muscular atrophy, Spinal and bulbar muscular atrophy (SBMA), Steroid 5 alpha reductase alpha polypeptide 1, Steroid 5 alpha reductase alpha polypeptide 1 (3 oxo 5 alpha steroid delta 4 dehydrogenase alpha 1), Steroid 5 alpha reductase type I, Steroid 5-alpha-reductase 1, Steroid 5-alpha-reductase 2, Steroid Delta-isomerase, Steroid and xenobiotic receptor, Steroid hormone receptor ERR1, Steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2), TFM, TOR, Testicular Feminization (TFM), Transcriptional activator GLI3, Transcriptional repressor GLI3R, Trophoblast antigen FDO161G, Type II 5-alpha reductase, Zinc finger protein GLI 3, androgen receptor splice variant 4b, e II 5 alpha reductase, erythroid derived 2, estrogen receptor related receptor alpha, hERR1, like 2, nuclear factor erythroid 2 like 2, pregnane X nuclear receptor variant 2, progressive familial intrahepatic cholestasis 2, trophoblast antigen