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AB142670

Floxuridine (5-Fluorodeoxyuridine), Antimetabolite antineoplastic agent

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MW 246.19 Da, Purity >99%. Prodrug. Antimetabolite antineoplastic agent. Shows more potent antineoplastic effects than analog, 5-Fluorouracil (Asc 2387). Shows antitumor effects in vivo. .
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Chemical Structure - Floxuridine (5-Fluorodeoxyuridine), Antimetabolite antineoplastic agent (AB142670)
  • Chemical Structure

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Chemical Structure - Floxuridine (5-Fluorodeoxyuridine), Antimetabolite antineoplastic agent (AB142670)

2D chemical structure image of ab142670, Floxuridine (5-Fluorodeoxyuridine), Antimetabolite antineoplastic agent

Key facts

CAS number

50-91-9

Purity

>99%

Form

Solid

form

Molecular weight

246.19 Da

Molecular formula

C<sub>9</sub>H<sub>1</sub><sub>1</sub>FN<sub>2</sub>O<sub>5</sub>

PubChem

5790

Nature

Synthetic

Solubility

Soluble in water to 100 mM

Soluble in ethanol to 100 mM

Soluble in DMSO to 100 mM

Biochemical name

Floxuridine

Biological description

Prodrug. Antimetabolite antineoplastic agent. Shows more potent antineoplastic effects than analog, 5-Fluorouracil (Asc 2387). Shows antitumor effects in vivo.

Canonical smiles

C1C(C(OC1N2C=C(C(=O)NC2=O)F)CO)O

Isomeric smiles

C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)F)CO)O

InChi

InChI=1S/C9H11FN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1

InChiKey

ODKNJVUHOIMIIZ-RRKCRQDMSA-N

IUPAC Name

5-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

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Complementary Products

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Biochemicals

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Biochemicals

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Assay Kits

AB270773

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months
Handling instructions

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Toxic, refer to SDS for further information.

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Product protocols

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Product promise

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