Fludarabine (FAMP), DNA synthesis inhibitor

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MW 285.23 Da, Purity >98%. DNA synthesis inhibitor. Prodrug converted to active metabolite F-ara-A which inhibits ribonucleotide reductase and competitively inhibits DNA polymerase. Also prevents DNA ligase I from joining DNA. Induces apoptosis. Active in vivo.

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A3AR, A3R, AA3R_HUMAN, AD 026, ADORA 3, AI838772, ARA3, ASL13, ATX2_HUMAN, AW493413, Adenosine A3 receptor, Adenosine receptor A3, Ataxin-2, Atxn2, Cytosolic NADP-isocitrate dehydrogenase, DKFZP586N0721, DKFZp686J10186, DNA replication inhibitor, Epididymis luminal protein 216, Epididymis secretory protein Li 26, FLJ11090, GEMI_HUMAN, GLP-1 receptor, GLP1R_HUMAN, GMNN, GPCR 2, Geminin, Geminin DNA replication inhibitor, Glucagon-like peptide 1 receptor, HEL-216, HEL-S-26, HSF1_HUMAN, HSPC193, HST17436, HSTF 1, Heat shock factor 1, Heat shock factor protein 1, Heat shock transcription factor 1, ICDH, IDCD, IDH, IDH1, IDHC_HUMAN, IDP, IDPC, Isocitrate dehydrogenase (NADP(+)) 1 cytosolic, Isocitrate dehydrogenase 1 (NADP+) soluble, Isocitrate dehydrogenase [NADP] cytoplasmic, JV15-2, LDS1C, LDS3, MAD (mothers against decapentaplegic Drosophila) homolog 3, MAD homolog 3, MAD, mothers against decapentaplegic homolog 3, MADH 3, MGC104252, MGC112732, MGC138331, MGC60396, Mad homolog JV15 2, Mad protein homolog, Mothers against DPP homolog 3, Mothers against decapentaplegic homolog 3, NADP dependent isocitrate dehydrogenase cytosolic, NADP dependent isocitrate dehydrogenase peroxisomal, NADP(+)-specific ICDH, NF-E2-related factor 2, NF2L2_HUMAN, NRF2, Nfe2l2, Nuclear factor, Nuclear factor (erythroid derived 2) like 2, Nuclear factor erythroid 2-related factor 2, Nuclear factor erythroid derived 2 like 2, OTTHUMP00000016340, OTTHUMP00000039393, Olivopontocerebellar ataxia 2, autosomal dominant, Oxalosuccinate decarboxylase, PICD, RP11 552M11.7, RP24-311F12.2, RP3 369A17.3, SCAN1, SMA and MAD related protein 3, SMAD, SMAD family member 3, SMAD, mothers against DPP homolog 3, SMAD3_HUMAN, Spinocerebellar ataxia type 2 protein, TGPCR1, TNRC13, TYDP, TYDP1_HUMAN, Trinucleotide repeat containing 13, Trinucleotide repeat-containing gene 13 protein, Tyr-DNA phosphodiesterase 1, Tyrosyl-DNA phosphodiesterase 1, bA552M11.5, erythroid derived 2, hMAD-3, hSMAD3, like 2, nuclear factor erythroid 2 like 2