MW 1129.85 g/mol, Purity >95%. Cell-permeable acetoxymethyl (AM) ester of the fluorescent calcium indicator Fluo-3. Commonly used in cell-based experiments to detect changes in intracellular calcium levels. Practically nonfluorescent until it is hydrolyzed intracellularly to Fluo-3 and in the presence of Ca2+.
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- Aging 13:9542-95652021Gastrodin ameliorates learning and memory impairment in rats with vascular dementia by promoting autophagy flux via inhibition of the Ca/CaMKII signal pathway.Applications:Unspecified applicationReactive species:Unspecified reactive speciesTing-Ting Chen,Xue Zhou,Yi-Ni Xu,Yue Li,Xiao-Ying Wu,Quan Xiang,Ling-Yun Fu,Xiao-Xia Hu,Ling Tao,Xiang-Chun ShenPubMed 33714957
- Clinical science (London, England : 1979) 135:793-8102021Soluble (pro)renin receptor induces endothelial dysfunction and hypertension in mice with diet-induced obesity via activation of angiotensin II type 1 receptor.Applications:Unspecified applicationReactive species:Unspecified reactive speciesZiwei Fu,Fei Wang,Xiyang Liu,Jiajia Hu,Jiahui Su,Xiaohan Lu,Aihua Lu,Jae Min Cho,J David Symons,Chang-Jiang Zou,Tianxin YangPubMed 33625485
- Oxidative medicine and cellular longevity 2020:73862392020Protective Effect of Epigallocatechin-3-Gallate in Hydrogen Peroxide-Induced Oxidative Damage in Chicken Lymphocytes.Applications:Unspecified applicationReactive species:Unspecified reactive speciesXiaoqing Chi et. al.PubMed 33488931
- Nature communications 11:18222020Obesity-induced overexpression of miR-802 impairs insulin transcription and secretion.Applications:Unspecified applicationReactive species:Unspecified reactive speciesFangfang Zhang et. al.PubMed 32286278
- Molecular medicine reports 20:1093-11022019Calcium‑sensing receptor promotes high glucose‑induced myocardial fibrosis via upregulation of the TGF‑β1/Smads pathway in cardiac fibroblasts.Applications:Unspecified applicationReactive species:Unspecified reactive speciesHui Yuan et. al.PubMed 31173208
- Cell death & disease 10:3412019Baicalein inhibits fibronectin-induced epithelial-mesenchymal transition by decreasing activation and upregulation of calpain-2.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYan Chen et. al.PubMed 31000696
Key facts
- CAS number
- 121714-22-5
- Purity
- > 95%
- Form
- Solid
- Molecular weight
- 1129.85 g/mol
- Molecular formula
- C51H50Cl2N2O23
- Nature
- Synthetic
- Excitation/Emission
- Ex: 506nm, Em: 526nm
Recommended products
MW 1129.85 g/mol, Purity >95%. Cell-permeable acetoxymethyl (AM) ester of the fluorescent calcium indicator Fluo-3. Commonly used in cell-based experiments to detect changes in intracellular calcium levels. Practically nonfluorescent until it is hydrolyzed intracellularly to Fluo-3 and in the presence of Ca2+.
Key facts
- CAS number
- 121714-22-5
- Purity
- > 95%
- Form
- Solid
- Molecular weight
- 1129.85 g/mol
- Molecular formula
- C51H50Cl2N2O23
- Nature
- Synthetic
- Solubility
Soluble in DMSO.
- Biological description
Cell-permeable acetoxymethyl (AM) ester of the fluorescent calcium indicator Fluo-3. Commonly used in cell-based experiments to detect changes in intracellular calcium levels. Practically nonfluorescent until it is hydrolyzed intracellularly to Fluo-3 and in the presence of Ca2+.
- InChI
- InChI=1S/C51H50Cl2N2O23/c1-28-7-9-39(54(19-47(62)74-24-69-30(3)57)20-48(63)75-25-70-31(4)58)45(13-28)66-11-12-67-46-14-34(8-10-40(46)55(21-49(64)76-26-71-32(5)59)22-50(65)77-27-72-33(6)60)51-35-15-37(52)41(61)17-42(35)78-43-18-44(38(53)16-36(43)51)73-23-68-29(2)56/h7-10,13-18H,11-12,19-27H2,1-6H3
- InChIKey
- PTPUOMXKXCCSEN-UHFFFAOYSA-N
- Excitation/Emission
- Ex: 506nm, Em: 526nm
Storage
- Shipped at conditions
- Ambient - Can Ship with Ice
- Appropriate short-term storage conditions
- -20°C
- Appropriate long-term storage conditions
- -20°C
- Storage information
- Store under desiccating conditions, The product can be stored for up to 12 months
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1 product image
Chemical Structure - Fluo-3 AM, Fluorescent calcium Indicator (ab145254)
2D chemical structure image of ab145254, Fluo-3 AM, Fluorescent calcium Indicator
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