Flupirtine maleate, Neuronal potassium channel opener

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MW 420.4 Da, Purity >99%. Neuronal potassium channel opener. Activates Kv7.2 channels and potently activates the inwardly rectifying potassium current (K_IR; EC₅₀ = 600 nM). Centrally acting, non-opiate analgesic. Neuroprotective and antiapoptotic agent. Also has muscle relaxant properties. Active in vivo.

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AI413597, AI838772, AW045860, AW493413, Atherosclerosis, susceptibility to, included, BLM_HUMAN, BS, Bloom syndrome, Bloom syndrome RecQ helicase like, Bloom syndrome protein, DDPAC, DKFZp686N23123, DNA helicase, DNA helicase RecQ like type 2, DNA polymerase eta, DNA polymerase iota, ER, ER-alpha, ER-beta, ERR a, ERR-alpha, ERR1 protein, ERR1_HUMAN, ER[a], ER[b], ESR, ESR B, ESR BETA, ESR1_HUMAN, ESRA, ESRL 1, ESRR A, ESTR B, Eag-related protein 1, Era, Erb, Erb2, Estr, Estra, Estradiol Receptor alpha, Estradiol Receptor beta, Estradiol receptor, Estrogen Receptor 1, Estrogen Receptor 2, Estrogen receptor, Estrogen receptor 1 (alpha), Estrogen receptor 2 (ER beta), Estrogen receptor 2 ER beta, Estrogen receptor alpha, Estrogen receptor beta 4, Estrogen receptor related 1, Estrogen receptor-like 1, Estrogen resistance, included, Estrogen-related receptor alpha, Estrra, Eta 2, Ether a go go related potassium channel protein, Ether-a-go-go-related gene potassium channel 1, Ether-a-go-go-related protein 1, FH, FLJ11090, FLJ16395, FLJ21978, FLJ31424, FTDP 17, FUMH_HUMAN, Fumarase, Fumarate hydratase, Fumarate hydratase mitochondrial, G protein beta1/gamma2 subunit interacting factor 1, H-ERG, HDL cholesterol, augmented response of, to hormone replacement, included, HLRCC, HSMPP8, KCNH2_HUMAN, Kv11.1, LQT 2, LRCC, M-phase phosphoprotein 8, M-phase phosphoprotein, mpp, M-phase phosphoprotein, mpp8, MAPT, MAPTL, MCL, MCUL 1, MGC104252, MGC112732, MGC126616, MGC131618, MGC131620, MGC134287, MGC138549, MGC156663, MPHOSPH8, MPP8_HUMAN, MS709, MSTD, MTBT1, MTBT2, Microtubule associated protein tau isoform 4, Microtubule-associated protein tau, Mtapt, Multiple hereditary cutaneous leiomyomata, Myocardial infarction, susceptibility to, included, NR3A1, NR3A2, NR3B1, Neurofibrillary tangle protein, Nuclear receptor subfamily 3 group A member 1, Nuclear receptor subfamily 3 group A member 2, Nuclear receptor subfamily 3 group B member 1, OTTHUMP00000017718, OTTHUMP00000017719, PHF-tau, POLH_HUMAN, POLI_HUMAN, PPND, PPP1R103, Paired helical filament-tau, Polymerase (DNA directed) iota, Potassium channel HERG, Potassium voltage gated channel subfamily H (eag related) member 2, Potassium voltage-gated channel subfamily H member 2, Protein phosphatase 1, regulatory subunit 103, RAD 30B, RAD30, RAD30 homolog A, RAD30 homolog B, RAD30, S. cerevisiae, homolog of, RAD30A, RAD3OB, RECQ 2, RECQ like, RECQL 2, RECQL 3, RNESTROR, RNPTAU, RP11-523H24.1, RP24-311F12.2, RecQ protein-like 3, RecQ-like type 2, SCAN1, SQT1, Steroid hormone receptor ERR1, TAU_HUMAN, TYDP, TYDP1_HUMAN, Tauopathy and respiratory failure, Tauopathy and respiratory failure, included, Twa3, Two hybrid-associated protein 3 with RanBPM, Tyr-DNA phosphodiesterase 1, Tyrosyl-DNA phosphodiesterase 1, Voltage gated potassium channel, subfamily H, member 2, Voltage-gated potassium channel subunit Kv11.1, XP V, Xeroderma pigmentosum variant type protein, eag homolog, estrogen receptor related receptor alpha, hERG-1, hERR1, pTau, polymerase DNA directed eta, type 2