MW 433.45 g/mol, Purity >99%. Competitive HMG-CoA reductase inhibitor (IC50 = 40 - 100 nM in human and rat microsomes). Potent inhibitor of vascular smooth muscle cell proliferation in vitro (IC50 = 70 nM).
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- Cell reports 37:1100562021Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMadeleine Dorsch,Manuela Kowalczyk,Mélanie Planque,Geronimo Heilmann,Sebastian Urban,Philip Dujardin,Jan Forster,Kristina Ueffing,Silke Nothdurft,Sebastian Oeck,Annika Paul,Sven T Liffers,Farnusch Kaschani,Markus Kaiser,Alexander Schramm,Jens T Siveke,Monte M Winslow,Sarah-Maria Fendt,Perihan Nalbant,Barbara M GrünerPubMed 34818551
Key facts
- CAS number
- 93957-55-2
- Purity
- > 99%
- Form
- Solid
- Molecular weight
- 433.45 g/mol
- Molecular formula
- C24H25FNNaO4
- Nature
- Synthetic
Recommended products
MW 433.45 g/mol, Purity >99%. Competitive HMG-CoA reductase inhibitor (IC50 = 40 - 100 nM in human and rat microsomes). Potent inhibitor of vascular smooth muscle cell proliferation in vitro (IC50 = 70 nM).
Key facts
- CAS number
- 93957-55-2
- Purity
- > 99%
- Form
- Solid
- Molecular weight
- 433.45 g/mol
- Molecular formula
- C24H25FNNaO4
- Nature
- Synthetic
- Solubility
Soluble in DMSO to 100 mM.
Soluble in water to 50 mM.
- Biological description
Competitive HMG-CoA reductase inhibitor (IC50 = 40 - 100 nM in human and rat microsomes). Potent inhibitor of vascular smooth muscle cell proliferation in vitro (IC50 = 70 nM).
- IUPAC name
- (±)-(3R*,5S*,6E)-7-[3-(4-Fluorophenyl)-1-(1-methyethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid sodium salt
Storage
- Shipped at conditions
- Ambient - Can Ship with Ice
- Appropriate short-term storage conditions
- -20°C
- Appropriate long-term storage conditions
- -20°C
- Storage information
- Store under desiccating conditions, The product can be stored for up to 12 months
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1 product image
Chemical Structure - Fluvastatin sodium salt, HMG-CoA reductase inhibitor (ab120651)
2D chemical structure image of ab120651, Fluvastatin sodium salt, HMG-CoA reductase inhibitor
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