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MW 410.5 Da. Cell-permeable activator of adenylyl cyclase. Interacts directly with the catalytic subunit of the enzyme to increase intracellular cAMP levels. Positive inotropic, platelet antiaggregatory and antihypertensive actions in vivo. 3D Growth matrix component used in liver organoid generation.
Alternative names=3',5'-cyclic AMP synthetase, AC1, AC2, ADCY1_HUMAN, ADH water channel, AQP-CD, AQP2_HUMAN, ATP pyrophosphate lyase 2, ATP pyrophosphate-lyase, ATP pyrophosphate-lyase 1, ATP pyrophosphate-lyase 8, Adenylate cyclase 1, Adenylate cyclase 1, fetal brain, type I, Adenylate cyclase 2, Adenylate cyclase 2 (brain), Adenylate cyclase 8, Adenylate cyclase II, Adenylate cyclase type 1, Adenylate cyclase type 2, Adenylate cyclase type I, Adenylate cyclase type II, Adenylate cyclase type VIII, Adenylyl cyclase 1, Adenylyl cyclase 8 brain, Aquaporin 2 collecting duct, Aquaporin-2, Aquaporin-CD, Aquaporine 2, BG 37, BXR, Brain adenylate cyclase 1, Brain adenylate cyclase 8, CSE, Ca(2+)/calmodulin-activated adenylyl cyclase, Choreoathetosis/spasticity episodic (paroxysmal choreoathetosis/spasticity), Collecting duct water channel protein, DFNB44, DKFZP586J0917, DYT17, DYT18, DYT9, EC 4.6.1.1, EIG12, Erythrocyte/hepatoma glucose transporter, FLJ16822, FLJ45092, FLJ99588, G protein coupled bile acid receptor BG 37, G-protein coupled bile acid receptor 1, G-protein coupled receptor GPCR19, GLUT, GLUT-1, GLUT1DS, GLUTB, GPBAR 1, GPBAR_HUMAN, GPCR, GPCR 19, GPR 131, GT1, GTG1, GTR1_HUMAN, Glucose transporter 1, Glucose transporter type 1, Glucose transporter type 1, erythrocyte/brain, Gm1018, Gtg3, HBAC1, HBAC2, HD 7, HD 7a, HDAC 7A, HDAC7_HUMAN, HTLVR, HepG2 glucose transporter, Histone deacetylase 7, Histone deacetylase 7A, Human T cell leukemia virus (I and II) receptor, KIAA1060, LGR 7, LGR7.1, LGR7.10, LGR7.2, Leucine-rich repeat-containing G-protein coupled receptor 7, M-BAR, MGC133314, MGC138347, MGC141895, MGC141896, MGC142177, MGC34501, MGC40597, Membrane bile acid receptor, Membrane-type receptor for bile acids, NR1I2_HUMAN, Nuclear receptor subfamily 1 group I member 2, ONR 1, OTTHUMP00000202813, OTTHUMP00000202814, OTTHUMP00000215173, OTTHUMP00000215174, OTTHUMP00000215175, Orphan nuclear receptor PAR 1, Orphan nuclear receptor PXR, PAR, PAR q, PED, PRR, Pregnane X receptor, RATGTG1, RXFP1_HUMAN, Receptor for HTLV 1 and HTLV 2, Relaxin family peptide receptor 1, Relaxin receptor 1, Relaxin/insulin like family peptide receptor 1, SXR, Solute carrier family 2, Solute carrier family 2 (facilitated glucose transporter), member 1, Solute carrier family 2, facilitated glucose transporter member 1, Steroid and xenobiotic receptor, TGR 5, Type II adenylate cyclase, WCH-CD, Water channel aquaporin 2, Water channel protein for renal collecting duct, adenyl cyclase, adenylate cyclase 1 (brain), deafness, autosomal recessive 44, erythrocyte/brain, facilitated glucose transporter member 1, hBG 37, hGPCR 19, pregnane X nuclear receptor variant 2
- CAS number
66575-29-9
- Form
Solid
- Source
Coleus forskohlii
- Molecular weight
410.5 Da
- Molecular formula
C22H34O7
- PubChem identifier
47936
- Nature
Native
Images
Target data
Recommended products
MW 410.5 Da. Cell-permeable activator of adenylyl cyclase. Interacts directly with the catalytic subunit of the enzyme to increase intracellular cAMP levels. Positive inotropic, platelet antiaggregatory and antihypertensive actions in vivo. 3D Growth matrix component used in liver organoid generation.
Alternative names=3',5'-cyclic AMP synthetase, AC1, AC2, ADCY1_HUMAN, ADH water channel, AQP-CD, AQP2_HUMAN, ATP pyrophosphate lyase 2, ATP pyrophosphate-lyase, ATP pyrophosphate-lyase 1, ATP pyrophosphate-lyase 8, Adenylate cyclase 1, Adenylate cyclase 1, fetal brain, type I, Adenylate cyclase 2, Adenylate cyclase 2 (brain), Adenylate cyclase 8, Adenylate cyclase II, Adenylate cyclase type 1, Adenylate cyclase type 2, Adenylate cyclase type I, Adenylate cyclase type II, Adenylate cyclase type VIII, Adenylyl cyclase 1, Adenylyl cyclase 8 brain, Aquaporin 2 collecting duct, Aquaporin-2, Aquaporin-CD, Aquaporine 2, BG 37, BXR, Brain adenylate cyclase 1, Brain adenylate cyclase 8, CSE, Ca(2+)/calmodulin-activated adenylyl cyclase, Choreoathetosis/spasticity episodic (paroxysmal choreoathetosis/spasticity), Collecting duct water channel protein, DFNB44, DKFZP586J0917, DYT17, DYT18, DYT9, EC 4.6.1.1, EIG12, Erythrocyte/hepatoma glucose transporter, FLJ16822, FLJ45092, FLJ99588, G protein coupled bile acid receptor BG 37, G-protein coupled bile acid receptor 1, G-protein coupled receptor GPCR19, GLUT, GLUT-1, GLUT1DS, GLUTB, GPBAR 1, GPBAR_HUMAN, GPCR, GPCR 19, GPR 131, GT1, GTG1, GTR1_HUMAN, Glucose transporter 1, Glucose transporter type 1, Glucose transporter type 1, erythrocyte/brain, Gm1018, Gtg3, HBAC1, HBAC2, HD 7, HD 7a, HDAC 7A, HDAC7_HUMAN, HTLVR, HepG2 glucose transporter, Histone deacetylase 7, Histone deacetylase 7A, Human T cell leukemia virus (I and II) receptor, KIAA1060, LGR 7, LGR7.1, LGR7.10, LGR7.2, Leucine-rich repeat-containing G-protein coupled receptor 7, M-BAR, MGC133314, MGC138347, MGC141895, MGC141896, MGC142177, MGC34501, MGC40597, Membrane bile acid receptor, Membrane-type receptor for bile acids, NR1I2_HUMAN, Nuclear receptor subfamily 1 group I member 2, ONR 1, OTTHUMP00000202813, OTTHUMP00000202814, OTTHUMP00000215173, OTTHUMP00000215174, OTTHUMP00000215175, Orphan nuclear receptor PAR 1, Orphan nuclear receptor PXR, PAR, PAR q, PED, PRR, Pregnane X receptor, RATGTG1, RXFP1_HUMAN, Receptor for HTLV 1 and HTLV 2, Relaxin family peptide receptor 1, Relaxin receptor 1, Relaxin/insulin like family peptide receptor 1, SXR, Solute carrier family 2, Solute carrier family 2 (facilitated glucose transporter), member 1, Solute carrier family 2, facilitated glucose transporter member 1, Steroid and xenobiotic receptor, TGR 5, Type II adenylate cyclase, WCH-CD, Water channel aquaporin 2, Water channel protein for renal collecting duct, adenyl cyclase, adenylate cyclase 1 (brain), deafness, autosomal recessive 44, erythrocyte/brain, facilitated glucose transporter member 1, hBG 37, hGPCR 19, pregnane X nuclear receptor variant 2
Key facts
- CAS number
66575-29-9
- Form
Solid
- Source
Coleus forskohlii
- Molecular weight
410.5 Da
- Molecular formula
C22H34O7
- PubChem identifier
47936
- Nature
Native
- Biochemical name
Forskolin
- Biological description
Cell-permeable activator of adenylyl cyclase. Interacts directly with the catalytic subunit of the enzyme to increase intracellular cAMP levels. Positive inotropic, platelet antiaggregatory and antihypertensive actions in vivo. 3D Growth matrix component used in liver organoid generation.
- Canonical SMILES
CC(=O)OC1C(C2C(CCC(C2(C3(C1(OC(CC3=O)(C)C=C)C)O)C)O)(C)C)O
- Isomeric SMILES
CC(=O)O[C@H]1[C@H]([C@@H]2[C@]([C@H](CCC2(C)C)O)([C@@]3([C@@]1(O[C@@](CC3=O)(C)C=C)C)O)C)O
- InChI
InChI=1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(26)17(28-12(2)23)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16-,17-,19-,20-,21+,22-/m0/s1
- InChIKey
OHCQJHSOBUTRHG-KGGHGJDLSA-N
- IUPAC name
[(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-5-yl] acetate
Storage
- Shipped at conditions
Ambient - Can Ship with Ice
- Appropriate long-term storage conditions
-20°C
- Storage information
Store under desiccating conditions, The product can be stored for up to 12 months
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