MW 832 Da, Purity >95%. Fluorescent Ca2+ binding dye. Binds to Ca2+ with high affinity (Kd = 225 nM in cytosol). Fluoresces green and fluorescence intensity increases upon Ca2+ binding. Cell membrane impermeable.
Excitation = 340/380 nm. Emission = 505 nm.
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- Molecular neurodegeneration 17:762022Upregulation of Ca-binding proteins contributes to VTA dopamine neuron survival in the early phases of Alzheimer's disease in Tg2576 mice.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLivia La Barbera,Annalisa Nobili,Emma Cauzzi,Ilaria Paoletti,Mauro Federici,Luana Saba,Cecilia Giacomet,Ramona Marino,Paraskevi Krashia,Marcello Melone,Flavio Keller,Nicola Biagio Mercuri,Maria Teresa Viscomi,Fiorenzo Conti,Marcello D'AmelioPubMed 36434727
- Nature communications 10:39452019Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson's disease.Applications:Unspecified applicationReactive species:Unspecified reactive speciesParaskevi Krashia et. al.PubMed 31477726
Key facts
- CAS number
- 113694-64-7
- Purity
- > 95%
- Form
- Solid
- Molecular weight
- 832 Da
- Molecular formula
- C29H22K5N3O14
- PubChem identifier
- 6098363
- Nature
- Synthetic
- Excitation/Emission
- Ex: 340nm, Em: 505nm
Recommended products
MW 832 Da, Purity >95%. Fluorescent Ca2+ binding dye. Binds to Ca2+ with high affinity (Kd = 225 nM in cytosol). Fluoresces green and fluorescence intensity increases upon Ca2+ binding. Cell membrane impermeable.
Excitation = 340/380 nm. Emission = 505 nm.
Key facts
- CAS number
- 113694-64-7
- Purity
- > 95%
- Form
- Solid
- Molecular weight
- 832 Da
- Molecular formula
- C29H22K5N3O14
- PubChem identifier
- 6098363
- Nature
- Synthetic
- Solubility
Soluble in water.
- Biochemical name
- Fura 2 pentapotassium salt, >=80%
- Biological description
Fluorescent Ca2+ binding dye. Binds to Ca2+ with high affinity (Kd = 225 nM in cytosol). Fluoresces green and fluorescence intensity increases upon Ca2+ binding. Cell membrane impermeable.
Excitation = 340/380 nm. Emission = 505 nm.- Canonical SMILES
- CC1=CC(=C(C=C1)N(CC(=O)[O-])CC(=O)[O-])OCCOC2=C(C=C3C(=C2)C=C(O3)C4=NC=C(O4)C(=O)[O-])N(CC(=O)[O-])CC(=O)[O-].[K+].[K+].[K+].[K+].[K+]
- InChI
- InChI=1S/C29H27N3O14.5K/c1-15-2-3-17(31(11-24(33)34)12-25(35)36)20(6-15)43-4-5-44-21-7-16-8-22(28-30-10-23(46-28)29(41)42)45-19(16)9-18(21)32(13-26(37)38)14-27(39)40;;;;;/h2-3,6-10H,4-5,11-14H2,1H3,(H,33,34)(H,35,36)(H,37,38)(H,39,40)(H,41,42);;;;;/q;5*+1/p-5
- InChIKey
- HQKWBBCTCLUGSX-UHFFFAOYSA-I
- IUPAC name
- pentapotassium;2-[6-[bis(carboxylatomethyl)amino]-5-[2-[2-[bis(carboxylatomethyl)amino]-5-methylphenoxy]ethoxy]-1-benzofuran-2-yl]-1,3-oxazole-5-carboxylate
- Excitation/Emission
- Ex: 340nm, Em: 505nm
Storage
- Shipped at conditions
- Ambient - Can Ship with Ice
- Appropriate short-term storage conditions
- -20°C
- Appropriate long-term storage conditions
- -20°C
- Storage information
- Store under desiccating conditions, The product can be stored for up to 12 months
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1 product image
Chemical Structure - Fura-2 K+ salt, fluorescent Ca2+ binding dye (ab142777)
2D chemical structure image of ab142777, Fura-2 K+ salt, fluorescent Ca2+binding dye
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