MW 692.7 Da. Aminoglycoside antibiotic agent. Potent Delta7-SMN target sequence inducer. Inhibits amino acid incorporation into proteins. Shows cytotoxic effects. Inhibits the prokaryotic and eukaryotic elongation cycle. Shows antibacterial and antiprotozoal effects in vivo. .
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- The EMBO journal 40:e1089032021The Hda1 histone deacetylase limits divergent non-coding transcription and restricts transcription initiation frequency.Applications:Unspecified applicationReactive species:Unspecified reactive speciesUthra Gowthaman,Maxim Ivanov,Isabel Schwarz,Heta P Patel,Niels A Müller,Desiré García-Pichardo,Tineke L Lenstra,Sebastian MarquardtPubMed 34661296
- Journal of cellular biochemistry 119:4420-44342018Silencing of COL1A2, COL6A3, and THBS2 inhibits gastric cancer cell proliferation, migration, and invasion while promoting apoptosis through the PI3k-Akt signaling pathway.Applications:Unspecified applicationReactive species:Unspecified reactive speciesRan Ao,Lin Guan,Ying Wang,Jia-Ni WangPubMed 29143985
Key facts
- CAS number
- 49662-05-7
- Form
- Solid
- Source
- Micromonospora rhodorangea
- Molecular weight
- 692.7 Da
- Molecular formula
- C20H44N4O18S2
- PubChem identifier
- 206347
- Nature
- Native
Target data
Recommended products
MW 692.7 Da. Aminoglycoside antibiotic agent. Potent Delta7-SMN target sequence inducer. Inhibits amino acid incorporation into proteins. Shows cytotoxic effects. Inhibits the prokaryotic and eukaryotic elongation cycle. Shows antibacterial and antiprotozoal effects in vivo. .
Key facts
- CAS number
- 49662-05-7
- Form
- Solid
- Source
- Micromonospora rhodorangea
- Molecular weight
- 692.7 Da
- Molecular formula
- C20H44N4O18S2
- PubChem identifier
- 206347
- Nature
- Native
- Solubility
Soluble in water to 100 mM.
- Biochemical name
- G-418 sulfate
- Biological description
Aminoglycoside antibiotic agent. Potent Delta7-SMN target sequence inducer. Inhibits amino acid incorporation into proteins. Shows cytotoxic effects. Inhibits the prokaryotic and eukaryotic elongation cycle. Shows antibacterial and antiprotozoal effects in vivo.
- Canonical SMILES
- CC(C1C(C(C(C(O1)OC2C(CC(C(C2O)OC3C(C(C(CO3)(C)O)NC)O)N)N)N)O)O)O.OS(=O)(=O)O.OS(=O)(=O)O
- Isomeric SMILES
- C[C@H]([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@H](C[C@H]([C@@H]([C@H]2O)O[C@@H]3[C@@H]([C@H]([C@@](CO3)(C)O)NC)O)N)N)N)O)O)O.OS(=O)(=O)O.OS(=O)(=O)O
- InChI
- InChI=1S/C20H40N4O10.2H2O4S/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19;2*1-5(2,3)4/h6-19,24-30H,4-5,21-23H2,1-3H3;2*(H2,1,2,3,4)/t6-,7+,8-,9-,10-,11+,12+,13-,14-,15-,16+,17-,18-,19-,20+;;/m1../s1
- InChIKey
- UHEPSJJJMTWUCP-DHDYTCSHSA-N
- IUPAC name
- (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-[(1R)-1-hydroxyethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol;sulfuric acid
Storage
- Shipped at conditions
- Ambient - Can Ship with Ice
- Appropriate short-term storage conditions
- -20°C
- Appropriate long-term storage conditions
- -20°C
- Storage information
- Store under desiccating conditions, The product can be stored for up to 12 months
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1 product image
Chemical Structure - G 418 sulfate (Geneticin sulfate), Aminoglycoside antibiotic agent (ab144261)
2D chemical structure image of ab144261, G 418 sulfate (Geneticin sulfate), Aminoglycoside antibiotic agent
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