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MW 602.8 Da, Purity >95%. Potent histone acetyltransferase p300 and PCAF inhibitor (IC50 values are 7 and 5 μM for p300 and PCAF respectively). Pleiotropic agent. Strongly inhibits chromatin transcription and induces apoptosis. Inhibits histone acetylation in vivo. Antioxidant and chemoprotective agent.
- CAS number
78824-30-3
- Purity
> 95%
- Molecular weight
602.8 Da
- Molecular formula
C38H50O6
- PubChem identifier
3531
- Nature
Synthetic
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MW 602.8 Da, Purity >95%. Potent histone acetyltransferase p300 and PCAF inhibitor (IC50 values are 7 and 5 μM for p300 and PCAF respectively). Pleiotropic agent. Strongly inhibits chromatin transcription and induces apoptosis. Inhibits histone acetylation in vivo. Antioxidant and chemoprotective agent.
Key facts
- CAS number
78824-30-3
- Purity
> 95%
- Molecular weight
602.8 Da
- Molecular formula
C38H50O6
- PubChem identifier
3531
- Nature
Synthetic
- Biochemical name
Camboginol
- Biological description
Potent histone acetyltransferase p300 and PCAF inhibitor (IC50 values are 7 and 5 μM for p300 and PCAF respectively). Pleiotropic agent. Strongly inhibits chromatin transcription and induces apoptosis. Inhibits histone acetylation in vivo. Antioxidant and chemoprotective agent.
- Canonical SMILES
CC(=CCC1CC2(C(=O)C(=C(C3=CC(=C(C=C3)O)O)O)C(=O)C(C2=O)(C1(C)C)CC=C(C)C)CC(CC=C(C)C)C(=C)C)C
- InChI
InChI=1S/C38H50O6/c1-22(2)11-13-27(25(7)8)20-37-21-28(15-12-23(3)4)36(9,10)38(35(37)44,18-17-24(5)6)34(43)31(33(37)42)32(41)26-14-16-29(39)30(40)19-26/h11-12,14,16-17,19,27-28,39-41H,7,13,15,18,20-21H2,1-6,8-10H3
- InChIKey
DTTONLKLWRTCAB-UHFFFAOYSA-N
- IUPAC name
3-[(3,4-dihydroxyphenyl)-hydroxymethylidene]-6,6-dimethyl-5,7-bis(3-methylbut-2-enyl)-1-(5-methyl-2-prop-1-en-2-ylhex-4-enyl)bicyclo[3.3.1]nonane-2,4,9-trione
Storage
- Shipped at conditions
Ambient - Can Ship with Ice
- Appropriate long-term storage conditions
-20°C
- Storage information
Store under desiccating conditions, The product can be stored for up to 12 months
Notes
This product is manufactured by BioVision, an Abcam company and was previously called 2088 Garcinol. 2088-25 is the same size as the 25 mg size of ab141503.
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