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AB141485

Gardiquimod, toll-like receptor 7 (TLR7) agonist

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MW 313.4 Da, Purity >98%. Selective TLR7 agonist. Inhibits HIV-1 reverse transcriptase. Induces pro-inflammatory cytokine production in thymocytes. Antiproliferative effects. Shows immunomodulatory effects in vivo. More active than Imiquimod (ab141410).
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Chemical Structure - Gardiquimod, toll-like receptor 7 (TLR7) agonist (AB141485)
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Chemical Structure - Gardiquimod, toll-like receptor 7 (TLR7) agonist (AB141485)

2D chemical structure image of ab141485, Gardiquimod, toll-like receptor 7 (TLR7) agonist

Key facts

CAS number

1020412-43-4

Purity

>98%

Form

Solid

form

Molecular weight

313.4 Da

Molecular formula

C<sub>1</sub><sub>7</sub>H<sub>2</sub><sub>3</sub>N<sub>5</sub>O

PubChem

44592366

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Biochemical name

Gardiquimod

Biological description

Selective TLR7 agonist. Inhibits HIV-1 reverse transcriptase. Induces pro-inflammatory cytokine production in thymocytes. Antiproliferative effects. Shows immunomodulatory effects in vivo. More active than Imiquimod (ab141410).

Canonical smiles

CCNCC1=NC2=C(N1CC(C)(C)O)C3=CC=CC=C3N=C2N

InChi

InChI=1S/C17H23N5O/c1-4-19-9-13-21-14-15(22(13)10-17(2,3)23)11-7-5-6-8-12(11)20-16(14)18/h5-8,19,23H,4,9-10H2,1-3H3,(H2,18,20)

InChiKey

FHJATBIERQTCTN-UHFFFAOYSA-N

IUPAC Name

1-[4-amino-2-(ethylaminomethyl)imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol

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Product details

This product is manufactured by BioVision, an Abcam company and was previously called 2002 Gardiquimod. 2002-25 is the same size as the 25 mg size of ab141485.
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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