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MW 375.4 Da, Purity >98%. Fluoroquinolone antibiotic. Inhibits bacterial DNA gyrase and type II topoisomerase (IC50 values are 0.109 and 13.8 μg/ml respectively. Pharmacologically active following oral administration. Crosses the blood-brain barrier.
Alternative names=1 25 dihydroxyvitamin D3 receptor, 25-dihydroxyvitamin D3 receptor, AI838772, AW493413, Atherosclerosis, susceptibility to, included, DKFZp686N23123, ER, ER-alpha, ER-beta, ER[a], ER[b], ESR, ESR B, ESR BETA, ESR1_HUMAN, ESRA, ESTR B, Era, Erb, Erb2, Estr, Estra, Estradiol Receptor alpha, Estradiol Receptor beta, Estradiol receptor, Estrogen Receptor 1, Estrogen Receptor 2, Estrogen receptor, Estrogen receptor 1 (alpha), Estrogen receptor 2 (ER beta), Estrogen receptor 2 ER beta, Estrogen receptor alpha, Estrogen receptor beta 4, Estrogen resistance, included, FLJ11090, HDL cholesterol, augmented response of, to hormone replacement, included, MGC104252, MGC112732, Member 1, Myocardial infarction, susceptibility to, included, NR1I1, NR3A1, NR3A2, Nuclear receptor subfamily 1 group I member 1, Nuclear receptor subfamily 3 group A member 1, Nuclear receptor subfamily 3 group A member 2, OTTHUMP00000017718, OTTHUMP00000017719, PPP1R163, Protein phosphatase 1, regulatory subunit 163, RNESTROR, RP24-311F12.2, SCAN1, TYDP, TYDP1_HUMAN, Tyr-DNA phosphodiesterase 1, Tyrosyl-DNA phosphodiesterase 1, VDR_HUMAN, Vitamin D (1,25- dihydroxyvitamin D3) receptor, Vitamin D hormone receptor, Vitamin D nuclear receptor variant 1, Vitamin D receptor, Vitamin D3 receptor
- CAS number
112811-59-3
- Purity
> 98%
- Form
Solid
- Molecular weight
375.4 Da
- Molecular formula
C19H22FN3O4
- PubChem identifier
5379
- Nature
Synthetic
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MW 375.4 Da, Purity >98%. Fluoroquinolone antibiotic. Inhibits bacterial DNA gyrase and type II topoisomerase (IC50 values are 0.109 and 13.8 μg/ml respectively. Pharmacologically active following oral administration. Crosses the blood-brain barrier.
Alternative names=1 25 dihydroxyvitamin D3 receptor, 25-dihydroxyvitamin D3 receptor, AI838772, AW493413, Atherosclerosis, susceptibility to, included, DKFZp686N23123, ER, ER-alpha, ER-beta, ER[a], ER[b], ESR, ESR B, ESR BETA, ESR1_HUMAN, ESRA, ESTR B, Era, Erb, Erb2, Estr, Estra, Estradiol Receptor alpha, Estradiol Receptor beta, Estradiol receptor, Estrogen Receptor 1, Estrogen Receptor 2, Estrogen receptor, Estrogen receptor 1 (alpha), Estrogen receptor 2 (ER beta), Estrogen receptor 2 ER beta, Estrogen receptor alpha, Estrogen receptor beta 4, Estrogen resistance, included, FLJ11090, HDL cholesterol, augmented response of, to hormone replacement, included, MGC104252, MGC112732, Member 1, Myocardial infarction, susceptibility to, included, NR1I1, NR3A1, NR3A2, Nuclear receptor subfamily 1 group I member 1, Nuclear receptor subfamily 3 group A member 1, Nuclear receptor subfamily 3 group A member 2, OTTHUMP00000017718, OTTHUMP00000017719, PPP1R163, Protein phosphatase 1, regulatory subunit 163, RNESTROR, RP24-311F12.2, SCAN1, TYDP, TYDP1_HUMAN, Tyr-DNA phosphodiesterase 1, Tyrosyl-DNA phosphodiesterase 1, VDR_HUMAN, Vitamin D (1,25- dihydroxyvitamin D3) receptor, Vitamin D hormone receptor, Vitamin D nuclear receptor variant 1, Vitamin D receptor, Vitamin D3 receptor
Key facts
- CAS number
112811-59-3
- Purity
> 98%
- Form
Solid
- Molecular weight
375.4 Da
- Molecular formula
C19H22FN3O4
- PubChem identifier
5379
- Nature
Synthetic
- Biochemical name
Gatifloxacin
- Biological description
Fluoroquinolone antibiotic. Inhibits bacterial DNA gyrase and type II topoisomerase (IC50 values are 0.109 and 13.8 μg/ml respectively. Pharmacologically active following oral administration. Crosses the blood-brain barrier.
- Canonical SMILES
CC1CN(CCN1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F
- InChI
InChI=1S/C19H22FN3O4/c1-10-8-22(6-5-21-10)16-14(20)7-12-15(18(16)27-2)23(11-3-4-11)9-13(17(12)24)19(25)26/h7,9-11,21H,3-6,8H2,1-2H3,(H,25,26)
- InChIKey
XUBOMFCQGDBHNK-UHFFFAOYSA-N
- IUPAC name
1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
Storage
- Shipped at conditions
Ambient - Can Ship with Ice
- Appropriate long-term storage conditions
+4°C
- Storage information
Store under desiccating conditions, The product can be stored for up to 12 months
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