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AB146435

GBR 13069 dihydrochloride, dopamine reuptake inhibitor

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MW 521.48 g/mol, Purity >99%. Potent dopamine reuptake inhibitor (IC50 = 40 nM). Inhibits noradrenaline reuptake (IC50 = 800 nM). Stimulates locomotor activity and shows central effects in vivo. .
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Chemical Structure - GBR 13069 dihydrochloride, dopamine reuptake inhibitor (AB146435)
  • Chemical Structure

Lab

Chemical Structure - GBR 13069 dihydrochloride, dopamine reuptake inhibitor (AB146435)

2D chemical structure image of ab146435, GBR 13069 dihydrochloride, dopamine reuptake inhibitor

Key facts

CAS number

67469-45-8

Purity

>99%

Form

Solid

form

Molecular weight

521.48 g/mol

Molecular formula

C<sub>2</sub><sub>8</sub>H<sub>3</sub><sub>0</sub>F<sub>2</sub>N<sub>2</sub>O.<sub>2</sub>HCl

Nature

Synthetic

Solubility

Soluble in water to 5 mM

Soluble in DMSO to 100 mM

Biological description

Potent dopamine reuptake inhibitor (IC50 = 40 nM). Inhibits noradrenaline reuptake (IC50 = 800 nM). Stimulates locomotor activity and shows central effects in vivo.

Isomeric smiles

C1CCC(CC1)/C=C/CN2CCN(CC2)CCOC(C3CCC(CC3)F)C4CCC(CC4)F.CL.CL

InChi

InChI=1S/C28H30F2N2O.2ClH/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23;;/h1-15,28H,16-22H2;2*1H/b7-4+;;

InChiKey

ZBSZWEYIIGLGSX-RDRKJGRWSA-N

IUPAC Name

1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenyl-2-propen-1-yl)piperazine dihydrochloride

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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