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MW 263.2 Da, Purity >98%. Cytidine analog. Antimetabolite. Induces apoptosis. Blocks cytosine nucleotide conversion into the deoxy derivative and blocks incorporation of the thymidine nucleotide into the DNA strand. Shows antitumor effects in vivo. .

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Images

Chemical Structure - Gemcitabine, Cytidine analog (AB145657), expandable thumbnail

Key facts

CAS number
95058-81-4
Purity
> 98%
Form
Solid
Molecular weight
263.2 Da
Molecular formula
C9H11F2N3O4
PubChem identifier
60750
Nature
Synthetic

Target data

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MW 263.2 Da, Purity >98%. Cytidine analog. Antimetabolite. Induces apoptosis. Blocks cytosine nucleotide conversion into the deoxy derivative and blocks incorporation of the thymidine nucleotide into the DNA strand. Shows antitumor effects in vivo. .

Key facts

Purity
> 98%
PubChem identifier
60750
Solubility

Soluble in DMSO to 50 mM.

Biochemical name
Gemcitabine
Biological description

Cytidine analog. Antimetabolite. Induces apoptosis. Blocks cytosine nucleotide conversion into the deoxy derivative and blocks incorporation of the thymidine nucleotide into the DNA strand. Shows antitumor effects in vivo.

Canonical SMILES
C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)(F)F
Isomeric SMILES
C1=CN(C(=O)N=C1N)[C@H]2C([C@@H]([C@H](O2)CO)O)(F)F
InChI
InChI=1S/C9H11F2N3O4/c10-9(11)6(16)4(3-15)18-7(9)14-2-1-5(12)13-8(14)17/h1-2,4,6-7,15-16H,3H2,(H2,12,13,17)/t4-,6-,7-/m1/s1
InChIKey
SDUQYLNIPVEERB-QPPQHZFASA-N
IUPAC name
4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions, The product can be stored for up to 12 months

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1 product image

  • Chemical Structure - Gemcitabine, Cytidine analog (ab145657), expandable thumbnail

    Chemical Structure - Gemcitabine, Cytidine analog (ab145657)

    2D chemical structure image of ab145657, Gemcitabine, Cytidine analog

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Product protocols

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