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AB145623

Gossypin, Chk1/Cdc25C activator

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MW 480.4 Da, Purity >98%. Chk1/Cdc25C activator. Antioxidant agent. Induces G2/M cell cycle arrest. Reduces lipid peroxidation. Shows antitumor, anti-ischemic and neuroprotective effects in vivo. Orally active.
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Chemical Structure - Gossypin, Chk1/Cdc25C activator (AB145623)
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Chemical Structure - Gossypin, Chk1/Cdc25C activator (AB145623)

2D chemical structure image of ab145623, Gossypin, Chk1/Cdc25C activator

Key facts

CAS number

652-78-8

Purity

>98%

Form

Solid

form

Source

Hibiscus vitifolius

Molecular weight

480.4 Da

Molecular formula

C<sub>2</sub><sub>1</sub>H<sub>2</sub><sub>0</sub>O<sub>1</sub><sub>3</sub>

PubChem

5281621

Nature

Native

Solubility

Soluble in DMSO to 25 mM

Biochemical name

Gossypin

Biological description

Chk1/Cdc25C activator. Antioxidant agent. Induces G2/M cell cycle arrest. Reduces lipid peroxidation. Shows antitumor, anti-ischemic and neuroprotective effects in vivo. Orally active.

Canonical smiles

C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C(=C(C=C3O)O)OC4C(C(C(C(O4)CO)O)O)O)O)O)O

Isomeric smiles

C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C(=C(C=C3O)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)O)O

InChi

InChI=1S/C21H20O13/c22-5-11-13(27)15(29)17(31)21(32-11)34-19-10(26)4-9(25)12-14(28)16(30)18(33-20(12)19)6-1-2-7(23)8(24)3-6/h1-4,11,13,15,17,21-27,29-31H,5H2/t11-,13-,15+,17-,21+/m1/s1

InChiKey

SJRXVLUZMMDCNG-KKPQBLLMSA-N

IUPAC Name

2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-8-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one

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Product details

This product is manufactured by BioVision, an Abcam company and was previously called 2374 Gossypin. 2374-250 is the same size as the 250 mg size of ab145623.
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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