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MW 442.5 Da, Purity >98%. Potent, broad spectrum PKC inhibitor (IC50 values are 7, 7, 6, 10, 60 and 20000 nM for PKCα, PKCβ, PKCγ, PKCδ, PKCζ and PKCμ respectively). Shows cardioprotective and anti-ischemic effects in vivo. .

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Publications

Key facts

CAS number
133053-19-7
Purity
> 98%
Form
Solid
Molecular weight
442.5 Da
Molecular formula
C26H26N4O3
PubChem identifier
3499
Nature
Synthetic

Target data

Alternative names

14-3-3-zetaisoform, AAG6, AI098070, Aging associated gene 6, Beta-interferon, C80388, CVID9, D14Ertd420e, EC 2.7.11.13, Fibroblast interferon, IFB, IFF, IFN, fibroblast, IFN-beta, IFNB 1, Interferon beta, KPCA_HUMAN, KPCB_HUMAN, KPCD_HUMAN, KPCG_HUMAN, KPCZ_HUMAN, Kinase PKC delta, May-01, MGC49908, MGC57564, MGC96956, OTTHUMP00000001368, OTTHUMP00000021131, OTTHUMP00000044160, OTTHUMP00000067291, PCKd, PKC 2, PKC ZETA, PKC d, PKC delta, PKC-A, PKC-B, PKC-alpha, PKC-beta, PKC-gamma, PKCC, PKCG, PKM-zeta, included, PRKACA, PRKC D, PRKC delta, PRKCA, PRKCB, PRKCB I, PRKCB II, PRKCB1, PRKCB2, PRKCG, PRKCZ, Pkcz, Protein Kinase C alpha, Protein Kinase C delta, Protein kinase C alpha type, Protein kinase C beta, Protein kinase C beta type, Protein kinase C delta VIII, Protein kinase C delta type, Protein kinase C gamma, Protein kinase C gamma polypeptide, Protein kinase C gamma type, Protein kinase C zeta, Protein kinase C zeta form, Protein kinase C zeta type, R74924, RP23-19G2.2, SCA 14, Tyrosine protein kinase PRKCD, aPKC, aPKCzeta, interferon beta 1, fibroblast, nPKC-delta, nPKC-zeta, protein kinase C, beta 1 polypeptide, protein kinase C, beta-1, r14-3-3, zetaPKC

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MW 442.5 Da, Purity >98%. Potent, broad spectrum PKC inhibitor (IC50 values are 7, 7, 6, 10, 60 and 20000 nM for PKCα, PKCβ, PKCγ, PKCδ, PKCζ and PKCμ respectively). Shows cardioprotective and anti-ischemic effects in vivo. .

Key facts

Purity
> 98%
PubChem identifier
3499
Biochemical name
3-[1-[3-(Dimethylamino)propyl]-5-methoxy-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione
Biological description

Potent, broad spectrum PKC inhibitor (IC50 values are 7, 7, 6, 10, 60 and 20000 nM for PKCα, PKCβ, PKCγ, PKCδ, PKCζ and PKCμ respectively). Shows cardioprotective and anti-ischemic effects in vivo.

Canonical SMILES
CN(C)CCCN1C=C(C2=C1C=CC(=C2)OC)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54
InChI
InChI=1S/C26H26N4O3/c1-29(2)11-6-12-30-15-20(18-13-16(33-3)9-10-22(18)30)24-23(25(31)28-26(24)32)19-14-27-21-8-5-4-7-17(19)21/h4-5,7-10,13-15,27H,6,11-12H2,1-3H3,(H,28,31,32)
InChIKey
LLJJDLHGZUOMQP-UHFFFAOYSA-N
IUPAC name
3-[1-[3-(dimethylamino)propyl]-5-methoxyindol-3-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dione

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions, The product can be stored for up to 12 months

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