MW 442.5 Da, Purity >98%. Potent, broad spectrum PKC inhibitor (IC50 values are 7, 7, 6, 10, 60 and 20000 nM for PKCα, PKCβ, PKCγ, PKCδ, PKCζ and PKCμ respectively). Shows cardioprotective and anti-ischemic effects in vivo. .
View Alternative Names
14-3-3-zetaisoform, AAG6, AI098070, Aging associated gene 6, Beta-interferon, C80388, CVID9, D14Ertd420e, EC 2.7.11.13, Fibroblast interferon, IFB, IFF, IFN, fibroblast, IFN-beta, IFNB 1, Interferon beta, KPCA_HUMAN, KPCB_HUMAN, KPCD_HUMAN, KPCG_HUMAN, KPCZ_HUMAN, Kinase PKC delta, May-01, MGC49908, MGC57564, MGC96956, OTTHUMP00000001368, OTTHUMP00000021131, OTTHUMP00000044160, OTTHUMP00000067291, PCKd, PKC 2, PKC ZETA, PKC d, PKC delta, PKC-A, PKC-B, PKC-alpha, PKC-beta, PKC-gamma, PKCC, PKCG, PKM-zeta, included, PRKACA, PRKC D, PRKC delta, PRKCA, PRKCB, PRKCB I, PRKCB II, PRKCB1, PRKCB2, PRKCG, PRKCZ, Pkcz, Protein Kinase C alpha, Protein Kinase C delta, Protein kinase C alpha type, Protein kinase C beta, Protein kinase C beta type, Protein kinase C delta VIII, Protein kinase C delta type, Protein kinase C gamma, Protein kinase C gamma polypeptide, Protein kinase C gamma type, Protein kinase C zeta, Protein kinase C zeta form, Protein kinase C zeta type, R74924, RP23-19G2.2, SCA 14, Tyrosine protein kinase PRKCD, aPKC, aPKCzeta, interferon beta 1, fibroblast, nPKC-delta, nPKC-zeta, protein kinase C, beta 1 polypeptide, protein kinase C, beta-1, r14-3-3, zetaPKC
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Publications (10)
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Nature protocols 19:1149-1182 PubMed38302732
2024
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The Journal of clinical investigation 133: PubMed37651195
2023
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eLife 10: PubMed34939930
2021
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Nature communications 11:6425 PubMed33349630
2020
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Autophagy :1-17 PubMed32762399
2020
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Journal of inflammation (London, England) 17:18 PubMed32377171
2020
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eLife 9: PubMed32352382
2020
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eLife 9: PubMed32234213
2020
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eLife 8: PubMed31210638
2019
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Cell stem cell 23:276-288.e8 PubMed30033119
2018
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