AB146660

GppCp (GMPPCP), Nonhydrolyzable GTP analog

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(4 Publications)

MW 521.21 g/mol, Purity >95%. Nonhydrolyzable GTP analog. Modulates G-protein cell signaling, protein synthesis and other metabolic processes. Forms stable protein complexes.

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Chemical Structure - GppCp (GMPPCP), Nonhydrolyzable GTP analog (AB146660)

Chemical Structure

Lab

Chemical Structure - GppCp (GMPPCP), Nonhydrolyzable GTP analog (AB146660)

2D chemical structure image of ab146660, GppCp (GMPPCP), Nonhydrolyzable GTP analog

Key facts

CAS number

10470-57-2

Purity

>95%

Molecular weight

521.21 g/mol

Molecular formula

C11H18N5O13P3

Nature

Synthetic

Solubility

Soluble in water to 75 mM

Biological description

Nonhydrolyzable GTP analog. Modulates G-protein cell signaling, protein synthesis and other metabolic processes. Forms stable protein complexes.

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Properties and storage information

Shipped at conditions

Ambient - Can Ship with Ice

Appropriate short-term storage conditions

-20°C

Appropriate long-term storage conditions

-20°C

Storage information

Store under desiccating conditions|The product can be stored for up to 12 months

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Product protocols

Visit the General protocols
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Publications (4)

Recent publications for all applications. Explore the full list and refine your search

microPublication biology 2025: PubMed40557276

2025

Rap1 activity and localization is regulated by Rab40/CRL5 facilitated mono-ubiquitylation.

Applications

Unspecified application

Species

Unspecified reactive species

Andrew Neumann,Revathi Sampath,Ke-Jun Han,Rytis Prekeris

BMC biology 22:264 PubMed39563372

2024

Motif-guided identification of KRAS-interacting proteins.

Applications

Unspecified application

Species

Unspecified reactive species

Sanan Wu,Xiaoyang Gao,Di Wu,Lu Liu,Han Yao,Xiangjun Meng,Xianglei Zhang,Fang Bai

Nature immunology 21:880-891 PubMed32541830

2020

Guanylate-binding proteins convert cytosolic bacteria into caspase-4 signaling platforms.

Applications

Unspecified application

Species

Unspecified reactive species

Michal P Wandel,Bae-Hoon Kim,Eui-Soon Park,Keith B Boyle,Komal Nayak,Brice Lagrange,Adrian Herod,Thomas Henry,Matthias Zilbauer,John Rohde,John D MacMicking,Felix Randow

The Journal of cell biology 217:997-1013 PubMed29420192

2018

Mechanism of Stx17 recruitment to autophagosomes via IRGM and mammalian Atg8 proteins.

Applications

Unspecified application

Species

Unspecified reactive species

Suresh Kumar,Ashish Jain,Farzin Farzam,Jingyue Jia,Yuexi Gu,Seong Won Choi,Michal H Mudd,Aurore Claude-Taupin,Michael J Wester,Keith A Lidke,Tor-Erik Rusten,Vojo Deretic

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Product promise

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GppCp (GMPPCP), Nonhydrolyzable GTP analog

Chemical Structure - GppCp (GMPPCP), Nonhydrolyzable GTP analog (AB146660)

Key facts

CAS number

Purity

Molecular weight

Molecular formula

Nature

Solubility

Biological description

Properties and storage information

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Storage information

Product protocols

Publications (4)

Complementary Products

Biochemicals

Secondary Antibodies

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