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AB120544

GR113808, selective 5-HT4 antagonist

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MW 393.5 g/mol, Purity >99%. Potent, highly selective 5-HT4 receptor antagonist (pKb = 8.8). Displays > 300-fold selectivity over 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2C and 5-HT3 receptors. Decreases water intake and potentiates drinking.
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Chemical Structure - GR113808, selective 5-HT4 antagonist (AB120544)
  • Chemical Structure

Lab

Chemical Structure - GR113808, selective 5-HT4 antagonist (AB120544)

2D chemical structure image of ab120544, GR113808, selective 5-HT4 antagonist

Key facts

CAS number

144625-51-4

Purity

>99%

Form

Solid

form

Molecular weight

393.5 g/mol

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Soluble in ethanol to 10 mM

Biological description

Potent, highly selective 5-HT4 receptor antagonist (pKb = 8.8). Displays > 300-fold selectivity over 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2C and 5-HT3 receptors. Decreases water intake and potentiates drinking.

IUPAC Name

[1-[2-[(Methylsulfonyl)amino]ethyl]-4-piperidinyl]methyl 1-methyl-1H-indole-3-carboxylate

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
The product can be stored for up to 12 months
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Product protocols

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Product promise

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