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AB144397

GSK-J5, Inactive control for GSK-J4

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(1 Publication)

MW 453.97 g/mol, Purity >97%. Cell-permeable, inactive control for histone demethylase JMJD3/UTX inhibitor GSK-J4 (ab144395). Active in vitro.
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Chemical Structure - GSK-J5, Inactive control for GSK-J4 (AB144397)
  • Chemical Structure

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Chemical Structure - GSK-J5, Inactive control for GSK-J4 (AB144397)

2D chemical structure image of ab144397, GSK-J5, Inactive control for GSK-J4

Key facts

CAS number

1394854-51-3

Purity

>97%

Form

Solid

form

Molecular weight

453.97 g/mol

Molecular formula

C<sub>2</sub><sub>4</sub>H<sub>2</sub><sub>7</sub>N<sub>5</sub>O<sub>2</sub>HCl

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Biological description

Cell-permeable, inactive control for histone demethylase JMJD3/UTX inhibitor GSK-J4 (ab144395). Active in vitro.

Canonical smiles

CL.O=C(OCC)CCNC1CC(NC(N1)C2CCCNC2)N3CCC4CCCCC4CC3

InChi

InChI=1S/C24H27N5O2.ClH/c1-2-31-23(30)9-13-26-21-16-22(28-24(27-21)20-8-5-12-25-17-20)29-14-10-18-6-3-4-7-19(18)11-15-29;/h3-8,12,16-17H,2,9-11,13-15H2,1H3,(H,26,27,28);1H

InChiKey

QQHQMHJAOKADED-UHFFFAOYSA-N

IUPAC Name

N-[2-(3-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Nature genetics 54:459-468 PubMed35410383

2022

H3K27me3 conditions chemotolerance in triple-negative breast cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Justine Marsolier,Pacôme Prompsy,Adeline Durand,Anne-Marie Lyne,Camille Landragin,Amandine Trouchet,Sabrina Tenreira Bento,Almut Eisele,Sophie Foulon,Léa Baudre,Kevin Grosselin,Mylène Bohec,Sylvain Baulande,Ahmed Dahmani,Laura Sourd,Eric Letouzé,Anne-Vincent Salomon,Elisabetta Marangoni,Leïla Perié,Céline Vallot
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