JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB146529

Guanosine 5'-diphosphate [GDP] disodium salt, Nucleoside diphosphate

Be the first to review this product! Submit a review

|

(5 Publications)

MW 487.17 g/mol, Purity >98%. Nucleoside diphosphate used as a substrate of pyruvate kinase to produce GTP in support of RNA biosynthesis. Used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Also used to study cell signaling processes mediate by guanine nucleotide exchange factors.
1 Images
Chemical Structure - Guanosine 5'-diphosphate [GDP] disodium salt, Nucleoside diphosphate (AB146529)
  • Chemical Structure

Lab

Chemical Structure - Guanosine 5'-diphosphate [GDP] disodium salt, Nucleoside diphosphate (AB146529)

2D chemical structure image of ab146529, Guanosine 5'-diphosphate [GDP] disodium salt, Nucleoside diphosphate

Key facts

CAS number

7415-69-2

Purity

>98%

Molecular weight

487.17 g/mol

Molecular formula

C<sub>1</sub><sub>0</sub>H<sub>1</sub><sub>3</sub>N<sub>5</sub>Na<sub>2</sub>O<sub>1</sub><sub>1</sub>P<sub>2</sub>

Nature

Synthetic

Solubility

Soluble in water to 100 mM

Biological description

Nucleoside diphosphate used as a substrate of pyruvate kinase to produce GTP in support of RNA biosynthesis. Used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Also used to study cell signaling processes mediate by guanine nucleotide exchange factors.

style
left-column

Complementary Products

Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Biochemicals

AB120674

DAMGO, mu opioid receptor agonist

Chemical Structure - DAMGO, mu opioid receptor agonist (AB120674)

  • 0
  • 0
Primary Antibodies

AB177487

Anti-NeuN antibody [EPR12763] - Neuronal Marker

BOND RX™ Validated|RabMAb|Recombinant|Lab Essentials|20ul selling size|Advanced Validation

Immunohistochemistry (Frozen sections) - Anti-NeuN antibody [EPR12763] - Neuronal Marker (AB177487)

  • 5
  • 74
Reagents, Controls & Accessories

AB119211

InstantBlue® Coomassie Protein Stain (ISB1L)

Western blot - InstantBlue® Coomassie Protein Stain (ISB1L) (AB119211)

  • 5
  • 5
style
left-column
style
left-column

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
style
left-column
style
left-column

Product protocols

style
left-column

Publications (5)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 14:4356 PubMed37468472

2023

Targeting an allosteric site in dynamin-related protein 1 to inhibit Fis1-mediated mitochondrial dysfunction.

Applications

Unspecified application

Species

Unspecified reactive species

Luis Rios,Suman Pokhrel,Sin-Jin Li,Gwangbeom Heo,Bereketeab Haileselassie,Daria Mochly-Rosen

Developmental cell 56:1000-1013.e6 PubMed33725482

2021

Mauve/LYST limits fusion of lysosome-related organelles and promotes centrosomal recruitment of microtubule nucleating proteins.

Applications

Unspecified application

Species

Unspecified reactive species

Ramona Lattao,Hélène Rangone,Salud Llamazares,David M Glover

The EMBO journal 39:e104926 PubMed32510692

2020

Direct binding of polymeric GBP1 to LPS disrupts bacterial cell envelope functions.

Applications

Unspecified application

Species

Unspecified reactive species

Miriam Kutsch,Linda Sistemich,Cammie F Lesser,Marcia B Goldberg,Christian Herrmann,Jörn Coers

Molecular cell 73:830-844.e12 PubMed30639242

2019

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

Applications

Unspecified application

Species

Unspecified reactive species

Joanna R Kovalski,Aparna Bhaduri,Ashley M Zehnder,Poornima H Neela,Yonglu Che,Glenn G Wozniak,Paul A Khavari

The Journal of cell biology 217:997-1013 PubMed29420192

2018

Mechanism of Stx17 recruitment to autophagosomes via IRGM and mammalian Atg8 proteins.

Applications

Unspecified application

Species

Unspecified reactive species

Suresh Kumar,Ashish Jain,Farzin Farzam,Jingyue Jia,Yuexi Gu,Seong Won Choi,Michal H Mudd,Aurore Claude-Taupin,Michael J Wester,Keith A Lidke,Tor-Erik Rusten,Vojo Deretic
View all publications
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com