GW1929, PPARgamma agonist

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(2 Publications)

MW 495.6 Da, Purity >98%. Potent, selective PPARγ agonist (EC₅₀ = 8 nM). Decreases glucose, fatty acid and triglyceride levels in vivo. Orally active.

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ARNT-interacting protein, Basic-helix-loop-helix-PAS protein MOP1, CP2D6_HUMAN, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, Cholesterol 25-hydroxylase, Class E basic helix-loop-helix protein 78, Cytochrome P450 2D6, Cytochrome P450 family 2 subfamily D member 6, Cytochrome P450 family 2 subfamily D polypeptide 6, Cytochrome P450-DB1, D-OR-1, Debrisoquine 4-hydroxylase, Delta type opioid receptor DOR 1, Delta-type opioid receptor, HIF-1, HIF-1-alpha, HIF-alpha, HIF1A_HUMAN, Hypoxia inducible factor 1 alpha isoform I.3, Hypoxia inducible factor 1 alpha subunit, Hypoxia inducible factor 1 alpha subunit basic helix loop helix transcription factor, Hypoxia inducible factor 1, alpha subunit (basic helix loop helix transcription factor), Hypoxia-inducible factor 1-alpha, MOP 1, Member of PAS protein 1, Member of PAS superfamily 1, Member of the PAS Superfamily 1, Microsomal monooxygenase, NR1C3, Nbor, Nuclear receptor subfamily 1 group C member 3, OPRD 1, OPRD_HUMAN, Opioid receptor delta 1, P450 DB1, P450C2D, PAS domain-containing protein 8, PASD 8, PPAR-gamma, PPARG2, PPARG_HUMAN, Peroxisome proliferator activated receptor gamma 2, Peroxisome proliferator-activated receptor gamma, Xenobiotic monooxygenase, bHLHe78, flavoprotein-linked monooxygenase, hifla, mDOR