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MW 483.81 g/mol, Purity >98%.

P2X7 allosteric modulator. Activity differs with species: acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 - 7.2) and a positive allosteric modulator of rat P2X7 receptors that increases the potency and effect of ATP.

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Images

Chemical Structure - GW791343, P2X7 allosteric modulator (AB120395), expandable thumbnail

Key facts

CAS number
1019779-04-4
Purity
> 98%
Form
Solid
Molecular weight
483.81 g/mol
Nature
Synthetic

Target data

Recommended products

MW 483.81 g/mol, Purity >98%.

P2X7 allosteric modulator. Activity differs with species: acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 - 7.2) and a positive allosteric modulator of rat P2X7 receptors that increases the potency and effect of ATP.

Key facts

Purity
> 98%
Solubility

Soluble in water to 100 mM.

Biological description

P2X7 allosteric modulator. Activity differs with species: acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 - 7.2) and a positive allosteric modulator of rat P2X7 receptors that increases the potency and effect of ATP.

IUPAC name
2-[(3,4-Difluorophenyl)amino]-N-[2-methyl-5-(1-piperazinylmethyl)phenyl]acetamide trihydrochloride

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
Store under desiccating conditions, The product can be stored for up to 12 months

Product promise

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1 product image

  • Chemical Structure - GW791343, P2X7 allosteric modulator (ab120395), expandable thumbnail

    Chemical Structure - GW791343, P2X7 allosteric modulator (ab120395)

    2D chemical structure image of ab120395, GW791343, P2X7 allosteric modulator

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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