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AB120395

GW791343, P2X7 allosteric modulator

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MW 483.81 g/mol, Purity >98%. P2X7 allosteric modulator. Activity differs with species: acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 - 7.2) and a positive allosteric modulator of rat P2X7 receptors that increases the potency and effect of ATP.
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Chemical Structure - GW791343, P2X7 allosteric modulator (AB120395)
  • Chemical Structure

Lab

Chemical Structure - GW791343, P2X7 allosteric modulator (AB120395)

2D chemical structure image of ab120395, GW791343, P2X7 allosteric modulator

Key facts

CAS number

1019779-04-4

Purity

>98%

Form

Solid

form

Molecular weight

483.81 g/mol

Nature

Synthetic

Solubility

Soluble in water to 100 mM

Biological description

P2X7 allosteric modulator. Activity differs with species: acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 - 7.2) and a positive allosteric modulator of rat P2X7 receptors that increases the potency and effect of ATP.

IUPAC Name

2-[(3,4-Difluorophenyl)amino]-N-[2-methyl-5-(1-piperazinylmethyl)phenyl]acetamide trihydrochloride

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Complementary Products

Biochemicals

AB120421

KN-62, CaM kinase II inhibitor. P2X7 antagonist.

Immunocytochemistry/ Immunofluorescence - KN-62, CaM kinase II inhibitor. P2X7 antagonist. (AB120421)

  • 0
  • 0
Primary Antibodies

AB52476

Anti-CaMKII antibody [EP1829Y]

RabMAb|Recombinant

Western blot - Anti-CaMKII antibody [EP1829Y] (AB52476)

  • 4
  • 7
Primary Antibodies

AB124880

Anti-CaMKII alpha (phospho T286) antibody [EPR1830]

BOND RX™ Validated|RabMAb|Recombinant|Trial Size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CaMKII alpha (phospho T286) antibody [EPR1830] (AB124880)

  • 5
  • 1
Primary Antibodies

AB181052

Anti-CaMKII delta antibody [EPR13095]

KO Validated|RabMAb|Recombinant

Western blot - Anti-CaMKII delta antibody [EPR13095] (AB181052)

  • 5
  • 1
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Product promise

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