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AB146132

H 9 dihydrochloride, Protein kinase inhibitor

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MW 324.2 Da, Purity >99%. Protein kinase inhibitor (Ki values are 0.9 (PKG), 1.9 (PKA), 18 (PKC), 60 (CaMK II), 110 (casein kinase I) and >300 μM (casein kinase II)) similar to H8 dihydrochloride (ab142309) and H7 (ab142308). Inhibits CTL-mediated lysis in vivo.
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Chemical Structure - H 9 dihydrochloride, Protein kinase inhibitor (AB146132)
  • Chemical Structure

Lab

Chemical Structure - H 9 dihydrochloride, Protein kinase inhibitor (AB146132)

2D chemical structure image of ab146132, H 9 dihydrochloride, Protein kinase inhibitor

Key facts

CAS number

116700-36-8

Purity

>99%

Form

Solid

form

Molecular weight

324.2 Da

Molecular formula

C<sub>1</sub><sub>1</sub>H<sub>1</sub><sub>5</sub>Cl<sub>2</sub>N<sub>3</sub>O<sub>2</sub>S

PubChem

11957465

Nature

Synthetic

Solubility

Soluble in water to 100 mM

Soluble in DMSO to 100 mM

Biochemical name

H-9 dihydrochloride

Biological description

Protein kinase inhibitor (Ki values are 0.9 (PKG), 1.9 (PKA), 18 (PKC), 60 (CaMK II), 110 (casein kinase I) and >300 μM (casein kinase II)) similar to H8 dihydrochloride (ab142309) and H7 (ab142308). Inhibits CTL-mediated lysis in vivo.

Canonical smiles

C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCN.Cl.Cl

InChi

InChI=1S/C11H13N3O2S.2ClH/c12-5-7-14-17(15,16)11-3-1-2-9-8-13-6-4-10(9)11;;/h1-4,6,8,14H,5,7,12H2;2*1H

InChiKey

HBLCYSFLYMHCBM-UHFFFAOYSA-N

IUPAC Name

N-(2-aminoethyl)isoquinoline-5-sulfonamide;dihydrochloride

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months
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Product protocols

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