H89 dihydrochloride, Kinase inhibitor

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(6 Publications)

MW 519.3 Da, Purity >98%. Kinase inhibitor, commonly used as a protein kinase A inhibitor (IC₅₀ = 135 nM). Also inhibits other kinases, including MSK1 , S6K1 and ROCKII (IC₅₀ values are 120, 80 and 270 nM, respectively).

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AKT, AKT2_HUMAN, AKT3 kinase, AKT3_HUMAN, DKFZp434N0250, HIHGHH, KAPCA_HUMAN, KIAA0619, MPPH, Oncogene AKT2 protein kinase B beta, PKA C-alpha, PKA C-beta, PKACA, PKACB, PKB, PKB beta, PKB-GAMMA, PKBB, PKBG, PPNAD4, PRKACA, PRKACAA, PRKACB, PRKBB, PRKBG, Protein kinase A catalytic subunit, Protein kinase A catalytic subunit alpha, Protein kinase A catalytic subunit beta, Protein kinase Akt-2, Protein kinase Akt-3, Protein kinase B beta, Protein kinase B gamma, Protein kinase cAMP dependent catalytic beta, Protein kinase, cAMP dependent, catalytic, alpha, RAC-BETA, RAC-PK-beta, RAC-PK-gamma, RAC-beta serine/threonine-protein kinase, RAC-gamma, RAC-gamma serine/threonine-protein kinase, ROCK2_HUMAN, ROK alpha, Rho associated coiled coil containing protein kinase 2, Rho associated, coiled coil containing protein kinase II, Rho kinase 2, Rho-associated, Rho-associated protein kinase 2, Rock II, Rock2m, STK-2, Serine threonine protein kinase Akt 3, V akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma), V akt murine thymoma viral oncogene homolog 3 protein kinase B gamma, V-AKT murine thymoma viral oncogene homolog 2, V-AKT murine thymoma viral oncogene homolog 3, cAMP dependent protein kinase alpha catalytic subunit, cAMP dependent protein kinase beta catalytic subunit, cAMP dependent protein kinase catalytic subunit alpha, isoform 1, cAMP-dependent protein kinase catalytic beta subunit isoform 4ab, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase catalytic subunit beta, coiled-coil-containing protein kinase 2, murine thymoma viral (v-akt) homolog-2, p164 ROCK-2, rac protein kinase beta