JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB120605

Harmane, beta-Carboline. Imidazoline ligand. MAO inhibitor.

Be the first to review this product! Submit a review

|

(0 Publication)

MW 182.22 g/mol, Purity >99%. Nanomolar affinity for the I1-imidazoline receptor (IC50 = 30 nM). Endogenous to the brain. Able to cross the blood-brain barrier. Active at I1, I2 and I3 binding sites, 1000-fold selectivity for I1 over α2 adrenoceptors. Known MAO-A inhibitor.
1 Images
Chemical Structure - Harmane, beta-Carboline. Imidazoline ligand. MAO inhibitor. (AB120605)
  • Chemical Structure

Lab

Chemical Structure - Harmane, beta-Carboline. Imidazoline ligand. MAO inhibitor. (AB120605)

2D chemical structure image of ab120605, Harmane, beta-Carboline. Imidazoline ligand. MAO inhibitor.

Key facts

CAS number

486-84-0

Purity

>99%

Form

Solid

form

Molecular weight

182.22 g/mol

Molecular formula

C<sub>1</sub><sub>2</sub>H<sub>1</sub><sub>0</sub>N<sub>2</sub>

Nature

Synthetic

Solubility

Soluble in ethanol to 100 mM

Soluble in DMSO to 100 mM

Biological description

Nanomolar affinity for the I1-imidazoline receptor (IC50 = 30 nM). Endogenous to the brain. Able to cross the blood-brain barrier. Active at I1, I2 and I3 binding sites, 1000-fold selectivity for I1 over α2 adrenoceptors. Known MAO-A inhibitor.

IUPAC Name

1-Methyl-9H-pyrido[3,4-b]indole

style
left-column

Complementary Products

Biochemicals

AB120297

Phorbol 12-myristate 13-acetate (PMA), PKC activator

Chemical Structure - Phorbol 12-myristate 13-acetate (PMA), PKC activator (AB120297)

  • 0
  • 0
Biochemicals

AB120451

Dipyridamole, Non-selective phosphodiesterase (PDE) inhibitor

Chemical Structure - Dipyridamole, Non-selective phosphodiesterase (PDE) inhibitor (AB120451)

  • 0
  • 0
Biochemicals

AB120189

alpha-MSH (alpha-Melanocyte-stimulating hormone), Endogenous melanocortin receptor agonist

Functional Studies - alpha-MSH (alpha-Melanocyte-stimulating hormone), Endogenous melanocortin receptor agonist (AB120189)

  • 0
  • 0
Biochemicals

AB120506

Cinnabarinic acid, Endogenous mGlu4 selective agonist

Chemical Structure - Cinnabarinic acid, Endogenous mGlu4 selective agonist (AB120506)

  • 0
  • 0
style
left-column
style
left-column

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months
style
left-column
style
left-column
style
left-column

Product protocols

style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com