HBDDE, PKCalpha and PKCgamma inhibitor

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(2 Publications)

MW 338.31 Da, Purity >97%. PKCα and PKCγ inhibitor (IC₅₀ values are 43 and 50 μM respectively). δ, βI and βII isotypes are not affected. Inducer of apoptosis. Active in vivo.

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AML 1, AML1 EVI 1, AML1 EVI 1 fusion protein, AMLCR 1, Acute myeloid leukemia 1, Acute myeloid leukemia 1 protein, Aml1 oncogene, CBF b, CBF-alpha-2, CBF-beta, CBFA 2, Core binding factor alpha 2 subunit, Core binding factor beta subunit, Core binding factor runt domain alpha subunit 2, Core-binding factor subunit alpha-2, Core-binding factor subunit beta, Core-binding factor, beta subunit (CBFB), transcript variant 2, DINB protein, DINB1, DINP, DNA damage inducible protein b, DNA polymerase kappa, DNase IV, DinB homolog 1 (E. coli), FEN1_HUMAN, Flap endonuclease 1, Flap structure-specific endonuclease 1, HGNC, MF1, Maturation factor 1, OTTHUMP00000108696, OTTHUMP00000108697, OTTHUMP00000108699, OTTHUMP00000108700, OTTHUMP00000108702, Oncogene AML-1, PEA 2, PEA2-alpha B, PEA2-beta, PEBB_HUMAN, PEBP 2B, PEBP2-alpha B, PEBP2-beta, PEBP2A2, PEBP2aB, POLK_HUMAN, POLQ, Polymerase (DNA directed) kappa, Polyomavirus enhancer-binding protein 2 alpha B subunit, Polyomavirus enhancer-binding protein 2 beta subunit, RUNX1_HUMAN, Rad2, Run1, Runt-related transcription factor 1, SL3 3 enhancer factor 1 beta subunit, SL3-3 enhancer factor 1 alpha B subunit, SL3-3 enhancer factor 1 subunit beta, SL3/AKV core-binding factor alpha B subunit, SL3/AKV core-binding factor beta subunit, alpha subunit core binding factor, hFEN-1, polymerase, DNA, kappa