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AB141250

Hydrocortisone, Adrenal glucocorticoid

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(13 Publications)

MW 362.5 Da, Purity >99%. Adrenal glucocorticoid. Stimulates gluconeogenesis, activates anxiolytic and anti-inflammatory pathways.
1 Images
Chemical Structure - Hydrocortisone, Adrenal glucocorticoid (AB141250)
  • Chemical Structure

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Chemical Structure - Hydrocortisone, Adrenal glucocorticoid (AB141250)

2D chemical structure image of ab141250, Hydrocortisone, Adrenal glucocorticoid

Key facts

CAS number

60103-17-5

Purity

>99%

Form

Solid

form

Molecular weight

362.5 Da

Molecular formula

C<sub>2</sub><sub>1</sub>H<sub>3</sub><sub>0</sub>O<sub>5</sub>

PubChem

108888

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Soluble in ethanol to 25 mM

Biochemical name

Timodine

Biological description

Adrenal glucocorticoid. Stimulates gluconeogenesis, activates anxiolytic and anti-inflammatory pathways.

Canonical smiles

CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)CO)O)C)O

Isomeric smiles

C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2C(C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)O

InChi

InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16?,18+,19-,20-,21-/m0/s1

InChiKey

JYGXADMDTFJGBT-KZUKIWJVSA-N

IUPAC Name

(8S,9S,10R,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one

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Complementary Products

Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Primary Antibodies

AB9485

Anti-GAPDH antibody - Loading Control

BOND RX™ Validated|Lab Essentials

Immunocytochemistry/ Immunofluorescence - Anti-GAPDH antibody - Loading Control (AB9485)

  • 5
  • 88
Primary Antibodies

AB1949

Anti-Cortisol antibody [XM210]

  • 0
  • 0
Assay Kits

AB108665

Cortisol ELISA Kit

Competitive ELISA - Cortisol ELISA Kit (AB108665)

  • 5
  • 4
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Publications (13)

Recent publications for all applications. Explore the full list and refine your search

Biomedical microdevices 27:17 PubMed40208377

2025

On-site analysis of cortisol in saliva based on microchannel lateral flow assay (mLFA) on polymer lab-on-a-chip (LOC).

Applications

Unspecified application

Species

Unspecified reactive species

V Thiyagarajan Upaassana,Supreeth Setty,Heeyeong Jang,Sthitodhi Ghosh,Chong Ahn

Micromachines 15: PubMed39459126

2024

Salivary Cortisol Detection with a Fully Inkjet-Printed Paper-Based Electrochemical Sensor.

Applications

Unspecified application

Species

Unspecified reactive species

Miguel Zea,Hamdi Ben Halima,Rosa Villa,Imad Abrao Nemeir,Nadia Zine,Abdelhamid Errachid,Gemma Gabriel

Environmental toxicology 39:583-591 PubMed37461228

2023

NIK-mediated reactivation of SIX2 enhanced the CSC-like traits of hepatocellular carcinoma cells through suppressing ubiquitin-proteasome system.

Applications

Unspecified application

Species

Unspecified reactive species

Liu Daren,Ye Dan,Wu Jinhong,Li Chao

Micromachines 13: PubMed36557534

2022

A Novel Cortisol Immunosensor Based on a Hafnium Oxide/Silicon Structure for Heart Failure Diagnosis.

Applications

Unspecified application

Species

Unspecified reactive species

Hamdi Ben Halima,Nadia Zine,Joan Bausells,Nicole Jaffrezic-Renault,Abdelhamid Errachid

Talanta 251:123759 PubMed35952499

2022

A novel electrochemical strategy for NT-proBNP detection using IMFET for monitoring heart failure by saliva analysis.

Applications

Unspecified application

Species

Unspecified reactive species

Hamdi Ben Halima,Francesca G Bellagambi,Marie Hangouët,Albert Alcacer,Norman Pfeiffer,Albert Heuberger,Nadia Zine,Joan Bausells,Abdelhamid Elaissari,Abdelhamid Errachid

Environmental toxicology 37:2366-2374 PubMed35730470

2022

Long non-coding RNA TDRG1 aggravates colorectal cancer stemness by binding with miR-873-5p to upregulate PRKAR2.

Applications

Unspecified application

Species

Unspecified reactive species

Qingqi Hong,Peishan Mai,Bin Wu,Haibin Wang,Mingzhe Xiao,Jun You

Environmental toxicology 37:2259-2268 PubMed35616188

2022

EHD1 promotes the cancer stem cell (CSC)-like traits of glioma cells via interacting with CD44 and suppressing CD44 degradation.

Applications

Unspecified application

Species

Unspecified reactive species

Yunhe Lu,Wei Wang,Shubin Tan

Environmental toxicology 37:2133-2142 PubMed35506701

2022

ISG15 enhances glioma cell stemness by promoting Oct4 protein stability.

Applications

Unspecified application

Species

Unspecified reactive species

Yuxiang Dai,Tianfu Yu,Chen Yu,Tianyu Lu,Lu Zhou,Chuandong Cheng,Hongbin Ni

Bioengineered 13:9959-9972 PubMed35416122

2022

MicroRNA-18 facilitates the stemness of gastric cancer by downregulating HMGB3 though targeting Meis2.

Applications

Unspecified application

Species

Unspecified reactive species

Yingjun Zhang,Weijian Lin,Weiping Jiang,Zhenfa Wang

Analytica chimica acta 1161:338468 PubMed33896556

2021

A silicon nitride ISFET based immunosensor for tumor necrosis factor-alpha detection in saliva. A promising tool for heart failure monitoring.

Applications

Unspecified application

Species

Unspecified reactive species

Hamdi Ben Halima,Francesca G Bellagambi,Albert Alcacer,Norman Pfeiffer,Albert Heuberger,Marie Hangouët,Nadia Zine,Joan Bausells,Abdelhamid Elaissari,Abdelhamid Errachid
View all publications
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