Skip to main content

MW 238.18 Da, Purity >98%. Insulin receptor tyrosine kinase inhibitor (IC50 = 100 μM). Inhibits serine and tyrosine autophosphorylation by the human insulin receptor. Membrane impermeable (membrane permeable analog available ab141567).

Be the first to review this product! Submit a review

Images

Chemical Structure - Hydroxy-2-naphthalenylmethylphosphonic acid (HNMPA), Insulin receptor tyrosine kinase inhibitor (AB141566), expandable thumbnail

Publications

  • Molecules and cells 32:389-952011
    Insulin contributes to fine-tuning of the pancreatic beta-cell response to glucagon-like peptide-1.
    Applications:
    Unspecified application
    Reactive species:
    Unspecified reactive species
    Mi Jin Moon et. al.
    PubMed 21904878
  • Proceedings of the National Academy of Sciences of the United States of America 89:7885-91992
    Catalysis of serine and tyrosine autophosphorylation by the human insulin receptor.
    Applications:
    Unspecified application
    Reactive species:
    Unspecified reactive species
    K Baltensperger,R E Lewis,C W Woon,P Vissavajjhala,A H Ross,M P Czech
    PubMed 1381504

Key facts

CAS number

120943-99-9

Purity

> 98%

Form

Solid

Molecular weight

238.18 Da

Molecular formula

C11H11O4P

PubChem identifier

129317

Nature

Synthetic

Target data

Recommended products

  1. Loading...
  2. Loading...
  3. Loading...
  4. Loading...

MW 238.18 Da, Purity >98%. Insulin receptor tyrosine kinase inhibitor (IC50 = 100 μM). Inhibits serine and tyrosine autophosphorylation by the human insulin receptor. Membrane impermeable (membrane permeable analog available ab141567).

Key facts

Purity

> 98%

PubChem identifier

129317

Solubility

Soluble in ethanol to 100 mM. Soluble in DMSO to 100 mM.

Biochemical name

(Hydroxy-2-naphthalenylmethyl)phosphonic acid

Biological description

Insulin receptor tyrosine kinase inhibitor (IC50 = 100 μM). Inhibits serine and tyrosine autophosphorylation by the human insulin receptor. Membrane impermeable (membrane permeable analog available ab141567).

Canonical SMILES

C1=CC=C2C=C(C=CC2=C1)C(O)P(=O)(O)O

InChI

InChI=1S/C11H11O4P/c12-11(16(13,14)15)10-6-5-8-3-1-2-4-9(8)7-10/h1-7,11-12H,(H2,13,14,15)

InChIKey

AMJJLDJPDLKNJA-UHFFFAOYSA-N

IUPAC name

[hydroxy(naphthalen-2-yl)methyl]phosphonic acid

Storage

Shipped at conditions

Ambient - Can Ship with Ice

Appropriate long-term storage conditions

-20°C

Storage information

Store under desiccating conditions, The product can be stored for up to 12 months

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

1 product image

  • Chemical Structure - Hydroxy-2-naphthalenylmethylphosphonic acid (HNMPA), Insulin receptor tyrosine kinase inhibitor (ab141566), expandable thumbnail

    Chemical Structure - Hydroxy-2-naphthalenylmethylphosphonic acid (HNMPA), Insulin receptor tyrosine kinase inhibitor (ab141566)

    2D chemical structure image of ab141566, Hydroxy-2-naphthalenylmethylphosphonic acid (HNMPA), Insulin receptor tyrosine kinase inhibitor

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com