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MW 238.18 Da, Purity >98%. Insulin receptor tyrosine kinase inhibitor (IC50 = 100 μM). Inhibits serine and tyrosine autophosphorylation by the human insulin receptor. Membrane impermeable (membrane permeable analog available ab141567).

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Images

Chemical Structure - Hydroxy-2-naphthalenylmethylphosphonic acid (HNMPA), Insulin receptor tyrosine kinase inhibitor (AB141566), expandable thumbnail

Key facts

CAS number
120943-99-9
Purity
> 98%
Form
Solid
Molecular weight
238.18 Da
Molecular formula
C11H11O4P
PubChem identifier
129317
Nature
Synthetic

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MW 238.18 Da, Purity >98%. Insulin receptor tyrosine kinase inhibitor (IC50 = 100 μM). Inhibits serine and tyrosine autophosphorylation by the human insulin receptor. Membrane impermeable (membrane permeable analog available ab141567).

Key facts

Purity
> 98%
PubChem identifier
129317
Solubility

Soluble in ethanol to 100 mM.

Soluble in DMSO to 100 mM.

Biochemical name
(Hydroxy-2-naphthalenylmethyl)phosphonic acid
Biological description

Insulin receptor tyrosine kinase inhibitor (IC50 = 100 μM). Inhibits serine and tyrosine autophosphorylation by the human insulin receptor. Membrane impermeable (membrane permeable analog available ab141567).

Canonical SMILES
C1=CC=C2C=C(C=CC2=C1)C(O)P(=O)(O)O
InChI
InChI=1S/C11H11O4P/c12-11(16(13,14)15)10-6-5-8-3-1-2-4-9(8)7-10/h1-7,11-12H,(H2,13,14,15)
InChIKey
AMJJLDJPDLKNJA-UHFFFAOYSA-N
IUPAC name
[hydroxy(naphthalen-2-yl)methyl]phosphonic acid

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions, The product can be stored for up to 12 months

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1 product image

  • Chemical Structure - Hydroxy-2-naphthalenylmethylphosphonic acid (HNMPA), Insulin receptor tyrosine kinase inhibitor (ab141566), expandable thumbnail

    Chemical Structure - Hydroxy-2-naphthalenylmethylphosphonic acid (HNMPA), Insulin receptor tyrosine kinase inhibitor (ab141566)

    2D chemical structure image of ab141566, Hydroxy-2-naphthalenylmethylphosphonic acid (HNMPA), Insulin receptor tyrosine kinase inhibitor

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Product protocols

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