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AB120827

Hydroxychloroquine sulfate, Anti-inflammatory and antimalarial agent

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(3 Publications)

MW 433.95 g/mol, Purity >99%. Anti-inflammatory, antimalarial and antirheumatic agent. Inhibits toll-like receptor 9 (IC50 = 80 nM). Active in vivo.
1 Images
Chemical Structure - Hydroxychloroquine sulfate, Anti-inflammatory and antimalarial agent (AB120827)
  • Chemical Structure

Lab

Chemical Structure - Hydroxychloroquine sulfate, Anti-inflammatory and antimalarial agent (AB120827)

2D chemical structure image of ab120827, Hydroxychloroquine sulfate, Anti-inflammatory and antimalarial agent

Key facts

CAS number

747-36-4

Purity

>99%

Form

Solid

form

Molecular weight

433.95 g/mol

Molecular formula

C<sub>1</sub><sub>8</sub>H<sub>2</sub><sub>6</sub>ClN<sub>3</sub>O.H<sub>2</sub>SO<sub>4</sub>

Nature

Synthetic

Solubility

Soluble in water to 100 mM

Biological description

Anti-inflammatory, antimalarial and antirheumatic agent. Inhibits toll-like receptor 9 (IC50 = 80 nM). Active in vivo.

IUPAC Name

7-Chloro-4-[4-[N-ethyl-N-(2-hydroxyethyl)amino]-1-methylbutylamino]quinoline sulfate

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
It is important to note that this product is reported to be light sensitive|Store in the dark|Store under desiccating conditions
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Product protocols

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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Archives of virology 168:147 PubMed37115342

2023

Repurposing of artesunate, an antimalarial drug, as a potential inhibitor of hepatitis E virus.

Applications

Unspecified application

Species

Unspecified reactive species

Neha Bhise,Megha Agarwal,Nidhi Thakur,P S Akshay,Sarah Cherian,Kavita Lole

Nature biomedical engineering 5:815-829 PubMed33941899

2021

A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics.

Applications

Unspecified application

Species

Unspecified reactive species

Longlong Si,Haiqing Bai,Melissa Rodas,Wuji Cao,Crystal Yuri Oh,Amanda Jiang,Rasmus Moller,Daisy Hoagland,Kohei Oishi,Shu Horiuchi,Skyler Uhl,Daniel Blanco-Melo,Randy A Albrecht,Wen-Chun Liu,Tristan Jordan,Benjamin E Nilsson-Payant,Ilona Golynker,Justin Frere,James Logue,Robert Haupt,Marisa McGrath,Stuart Weston,Tian Zhang,Roberto Plebani,Mercy Soong,Atiq Nurani,Seong Min Kim,Danni Y Zhu,Kambez H Benam,Girija Goyal,Sarah E Gilpin,Rachelle Prantil-Baun,Steven P Gygi,Rani K Powers,Kenneth E Carlson,Matthew Frieman,Benjamin R tenOever,Donald E Ingber

Journal of gynecologic oncology 28:e33 PubMed28382796

2017

Inhibition of autophagy protein LC3A as a therapeutic target in ovarian clear cell carcinomas.

Applications

Unspecified application

Species

Unspecified reactive species

Morikazu Miyamoto,Masashi Takano,Tadashi Aoyama,Hiroaki Soyama,Tomoyuki Yoshikawa,Hitoshi Tsuda,Kenichi Furuya
View all publications
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