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MW 504.4 Da, Purity >97%. Selective PKC inhibitor (IC50 = 3.3 μM). Antiviral agent. Potent tyrosine kinase inhibitor (IC50 = 7.5 μM). Potent CKII inhibitor (IC50 = 6 nM). Inactivates enveloped viruses including HIV. Promotes VEGF and TGF-β production. Shows photosensitizing and antidepressant effects in vivo. .

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Images

Chemical Structure - Hypericin, PKC inhibitor (AB142440), expandable thumbnail

Key facts

CAS number
548-04-9
Purity
> 97%
Form
Solid
Source
Hypericum perforatum
Molecular weight
504.4 Da
Molecular formula
C30H16O8
PubChem identifier
5281051
Nature
Native

Target data

Recommended products

MW 504.4 Da, Purity >97%. Selective PKC inhibitor (IC50 = 3.3 μM). Antiviral agent. Potent tyrosine kinase inhibitor (IC50 = 7.5 μM). Potent CKII inhibitor (IC50 = 6 nM). Inactivates enveloped viruses including HIV. Promotes VEGF and TGF-β production. Shows photosensitizing and antidepressant effects in vivo. .

Key facts

Purity
> 97%
Source
Hypericum perforatum
PubChem identifier
5281051
Solubility

Soluble in DMSO to 50 mM.

Soluble in ethanol to 10 mM (with warming).

Biochemical name
CID 5281051
Biological description

Selective PKC inhibitor (IC50 = 3.3 μM). Antiviral agent. Potent tyrosine kinase inhibitor (IC50 = 7.5 μM). Potent CKII inhibitor (IC50 = 6 nM). Inactivates enveloped viruses including HIV. Promotes VEGF and TGF-β production. Shows photosensitizing and antidepressant effects in vivo.

Canonical SMILES
CC1=CC(=C2C3=C4C5=C(C(=CC(=C5C2=O)O)O)C6=C7C4=C8C(=C13)C(=CC(=C8C(=O)C7=C(C=C6O)O)O)C)O
Isomeric SMILES
CC1=CC(=C2C3=C4C5=C(C(=CC(=C5C2=O)O)O)C6=C7C4=C8C(=C13)C(=CC(=C8C(=O)C7=C(C=C6O)O)O)C)O
InChI
InChI=1S/C30H16O8/c1-7-3-9(31)19-23-15(7)16-8(2)4-10(32)20-24(16)28-26-18(12(34)6-14(36)22(26)30(20)38)17-11(33)5-13(35)21(29(19)37)25(17)27(23)28/h3-6,31-36H,1-2H3
InChIKey
BTXNYTINYBABQR-UHFFFAOYSA-N
IUPAC name
5,7,11,18,22,24-hexahydroxy-13,16-dimethyloctacyclo[13.11.1.12,10.03,8.04,25.019,27.021,26.014,28]octacosa-1(27),2(28),3,5,7,10,12,14,16,18,21,23,25-tridecaene-9,20-dione

Storage

Shipped at conditions
Blue Ice
Appropriate long-term storage conditions
+4°C
Storage information
Store under desiccating conditions, The product can be stored for up to 12 months

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1 product image

  • Chemical Structure - Hypericin, PKC inhibitor (ab142440), expandable thumbnail

    Chemical Structure - Hypericin, PKC inhibitor (ab142440)

    2D chemical structure image of ab142440, Hypericin, PKC inhibitor

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Product protocols

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