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MW 313.9 Da, Purity >99%. Highly selective β2 adrenoceptor antagonist (Ki values are 1.2, 120 and 257 nM at β2, β1 and β3 receptors, respectively). Blood-brain barrier permeable. Decreases vascular tone *in vivo*.

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Images

Chemical Structure - ICI 118551 hydrochloride, beta2 adrenoceptor antagonist (AB120808), expandable thumbnail

Publications

Key facts

CAS number

72795-04-1

Purity

> 99%

Form

Solid

Molecular weight

313.9 Da

Molecular formula
C17H28ClNO2
PubChem identifier

25102594

Nature

Synthetic

Recommended products

MW 313.9 Da, Purity >99%. Highly selective β2 adrenoceptor antagonist (Ki values are 1.2, 120 and 257 nM at β2, β1 and β3 receptors, respectively). Blood-brain barrier permeable. Decreases vascular tone *in vivo*.

Key facts

Purity

> 99%

PubChem identifier

25102594

Solubility

Soluble in water to 10 mM. Soluble in DMSO to 10 mM.

Biochemical name

ICI 118,551 hydrochloride

Biological description

Highly selective β2 adrenoceptor antagonist (Ki values are 1.2, 120 and 257 nM at β2, β1 and β3 receptors, respectively). Blood-brain barrier permeable. Decreases vascular tone *in vivo*.

Canonical SMILES

CC1=C2CCCC2=C(C=C1)OCC(C(C)NC(C)C)O.Cl

Isomeric SMILES

CC1=C2CCCC2=C(C=C1)OC[C@@H]([C@H](C)NC(C)C)O.Cl

InChI

InChI=1S/C17H27NO2.ClH/c1-11(2)18-13(4)16(19)10-20-17-9-8-12(3)14-6-5-7-15(14)17;/h8-9,11,13,16,18-19H,5-7,10H2,1-4H3;1H/t13-,16-;/m0./s1

InChIKey

KBXMBGWSOLBOQM-LINSIKMZSA-N

IUPAC name

(2R,3S)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]-3-(propan-2-ylamino)butan-2-ol;hydrochloride

Storage

Shipped at conditions

Ambient - Can Ship with Ice

Appropriate short-term storage conditions

Ambient

Appropriate long-term storage conditions

Ambient

Storage information

Store under desiccating conditions, The product can be stored for up to 12 months

Product promise

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1 product image

  • Chemical Structure - ICI 118551 hydrochloride, beta2 adrenoceptor antagonist (ab120808), expandable thumbnail

    Chemical Structure - ICI 118551 hydrochloride, beta2 adrenoceptor antagonist (ab120808)

    2D chemical structure image of ab120808, ICI 118551 hydrochloride, beta2 adrenoceptor antagonist

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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