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AB142141

iCRT5, CRT Inhibitor, CRT inhibitor

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(1 Publication)

MW 367.44 g/mol, Purity >98%. Cell-permeable β-catenin-responsive transcription (CRT) inhibitor. Wnt responsive STF16 luciferase inhibitor (IC50 = 18 nM). Active in vitro.
1 Images
Chemical Structure - iCRT5, CRT Inhibitor, CRT inhibitor (AB142141)
  • Chemical Structure

Lab

Chemical Structure - iCRT5, CRT Inhibitor, CRT inhibitor (AB142141)

2D chemical structure image of ab142141, iCRT5, CRT Inhibitor, CRT inhibitor

Key facts

CAS number

18623-44-4

Purity

>98%

Form

Solid

form

Molecular weight

367.44 g/mol

Molecular formula

C<sub>1</sub><sub>6</sub>H<sub>1</sub><sub>7</sub>NO<sub>5</sub>S<sub>2</sub>

Nature

Synthetic

Solubility

Soluble in DMSO

Biological description

Cell-permeable β-catenin-responsive transcription (CRT) inhibitor. Wnt responsive STF16 luciferase inhibitor (IC50 = 18 nM). Active in vitro.

IUPAC Name

(Z)-4-(5-(3,4-Dimethoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)butanoic acid

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Complementary Products

Primary Antibodies

AB91654

Anti-CRTC3 antibody [EPR3440]

RabMAb|Recombinant|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CRTC3 antibody [EPR3440] (AB91654)

  • 5
  • 2
Biochemicals

AB144637

CRT0066101, protein kinase D inhibitor

Chemical Structure - CRT0066101, protein kinase D inhibitor (AB144637)

  • 0
  • 0
Primary Antibodies

AB92516

Anti-Calreticulin antibody [EPR3924] - ER Marker

BOND RX™ Validated|RabMAb|Recombinant|KO Validated|Lab Essentials

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Calreticulin antibody [EPR3924] - ER Marker (AB92516)

  • 4
  • 6
Primary Antibodies

AB273884

Anti-CRTAM antibody [EPR23786-12] - BSA and Azide free

RabMAb|Recombinant

Flow Cytometry - Anti-CRTAM antibody [EPR23786-12] - BSA and Azide free (AB273884)

  • 0
  • 0
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Product details

This product is manufactured by BioVision, an Abcam company and was previously called 1896 CRT Inhibitor, iCRT5. 1896-25 is the same size as the 25 mg size of ab142141.
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Journal of nanobiotechnology 22:647 PubMed39434141

2024

Co-delivery of polyphyllin II and IR780 PLGA nanoparticles induced pyroptosis combined with photothermal to enhance hepatocellular carcinoma immunotherapy.

Applications

Unspecified application

Species

Unspecified reactive species

Huating Huang,Jing Fu,Hulinyue Peng,Yuanyuan He,Aqian Chang,Huizhong Zhang,Yang Hao,Xiaohan Xu,Shiman Li,Jingxia Zhao,Jian Ni,Xiaoxv Dong
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Product promise

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