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MW 240.3 Da, Purity >98%. Cell-permeable definitive endoderm formation inducer (EC50 = 223 nM, induction of Sox17 expression in ESCs) similar to IDE 1 (ab145222). Activates TGF-β signaling and downstream Smad2 phosphorylation. Upregulates Nodal expression. Induces gut tube formation in vivo. .
- CAS number
1136466-93-7
- Purity
> 98%
- Molecular weight
240.3 Da
- Molecular formula
C12H20N2O3
- PubChem identifier
23836158
- Nature
Synthetic
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MW 240.3 Da, Purity >98%. Cell-permeable definitive endoderm formation inducer (EC50 = 223 nM, induction of Sox17 expression in ESCs) similar to IDE 1 (ab145222). Activates TGF-β signaling and downstream Smad2 phosphorylation. Upregulates Nodal expression. Induces gut tube formation in vivo. .
Key facts
- CAS number
1136466-93-7
- Purity
> 98%
- Molecular weight
240.3 Da
- Molecular formula
C12H20N2O3
- PubChem identifier
23836158
- Nature
Synthetic
- Biochemical name
7-(2-Cyclopentylidenehydrazinyl)-7-oxoheptanoic acid
- Biological description
Cell-permeable definitive endoderm formation inducer (EC50 = 223 nM, induction of Sox17 expression in ESCs) similar to IDE 1 (ab145222). Activates TGF-β signaling and downstream Smad2 phosphorylation. Upregulates Nodal expression. Induces gut tube formation in vivo.
- Canonical SMILES
C1CCC(=NNC(=O)CCCCCC(=O)O)C1
- InChI
InChI=1S/C12H20N2O3/c15-11(8-2-1-3-9-12(16)17)14-13-10-6-4-5-7-10/h1-9H2,(H,14,15)(H,16,17)
- InChIKey
CVYPYYPTFNVREL-UHFFFAOYSA-N
- IUPAC name
7-(2-cyclopentylidenehydrazinyl)-7-oxoheptanoic acid
Storage
- Shipped at conditions
Ambient - Can Ship with Ice
- Appropriate long-term storage conditions
-20°C
- Storage information
Store under desiccating conditions, The product can be stored for up to 12 months
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