MW 482.5 Da, Purity >=98%. IITZ-01 (ab287028) is a potent lysosomotropic autophagy inhibitor; displays >10-fold potent autophagy inhibition than Chloroquine; enhances autophagosome accumulation but inhibits autophagosomal degradation by impairing lysosomal function, finally resulting in the inhibition of autophagy. Displays potent anticancer activity.
MW 482.5 Da, Purity >=98%. IITZ-01 (ab287028) is a potent lysosomotropic autophagy inhibitor; displays >10-fold potent autophagy inhibition than Chloroquine; enhances autophagosome accumulation but inhibits autophagosomal degradation by impairing lysosomal function, finally resulting in the inhibition of autophagy. Displays potent anticancer activity.
Soluble in DMSO to >100 mM.
IITZ-01 (ab287028) is a potent lysosomotropic autophagy inhibitor; displays >10-fold potent autophagy inhibition than Chloroquine; enhances autophagosome accumulation but inhibits autophagosomal degradation by impairing lysosomal function, finally resulting in the inhibition of autophagy. Displays potent anticancer activity.
This product is manufactured by BioVision, an Abcam company and was previously called B2378 IITZ-01. B2378-5 is the same size as the 5 mg size of ab287028.
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